sudo raspi-config - Choose Interfacing Options -> SPI -> Yes Enable SPI interface sudo apt-get install git git clone https://github.com/AbnormalDistributions/e_paper_weather_display.git sudo apt install python3-pillow python3-requests python3-pil git clone https://github.com/waveshare/e-Paper.git Replace this line in weather.py (thanks chairstacker) - lib_path = os.path.join(script_dir, 'lib' with this line - lib_path = "/home/pi/_e-Paper/RaspberryPi_JetsonNano/python/lib" # Set according to your git download Update weather.py as per instructions with api, lat & lon etc. python weather.py