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I can speak to this issue as I was having similar problems in the last year due to moving to python 3.8 (and recently 10). In Python 3.8, they changed how DLL resolution can safely be handled on Windows. I recommend reviewing this post which poses the generic problem of DLL loading and the one answer cites the Python 3.8 What’s New Docs as well as an example of setting it using the os.add_dll_directory() function. Basically modifying the PATH env var will no longer work in 3.8+ for DLL resolution (It of course still works in 3.7 and older).

https://stackoverflow.com/questions/214852/python-module-dlls

Another thing I’ve done in my VCPKG build testing is that the PYD and DLLs are in separa…

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@mexxmillion
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@stereorobin
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