diff --git a/cmake/dependencies/python3.cmake b/cmake/dependencies/python3.cmake
index f3cb2e3c1..412494dca 100644
--- a/cmake/dependencies/python3.cmake
+++ b/cmake/dependencies/python3.cmake
@@ -288,7 +288,7 @@ SET(_requirements_install_command
     ${CMAKE_COMMAND} -E env
     ${_otio_debug_env}
     "CMAKE_ARGS=-DPYTHON_LIBRARY=${_python3_cmake_library} -DPYTHON_INCLUDE_DIR=${_include_dir} -DPYTHON_EXECUTABLE=${_python3_executable}"
-    "${_python3_executable}" -m pip install --upgrade --no-cache-dir --force-reinstall -r "${_requirements_output_file}"
+    "${_python3_executable}" -s -E -I -m pip install --upgrade --no-cache-dir --force-reinstall -r "${_requirements_output_file}"
 )
 
 IF(RV_TARGET_WINDOWS)
diff --git a/requirements.txt b/requirements.txt
index 068b9c105..9597ec28a 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -7,5 +7,4 @@ pyzstd==0.15.9; python_version <= '3.8'  # License: BSD License (BSD-3-Clause)
 pyzstd; python_version > '3.8'           # License: BSD License (BSD-3-Clause)
 py7zr==0.22.0; python_version <= '3.8'   # License: GNU Lesser General  Public License v2 or later (LGPLv2+) (LGPL-2.1-or-later)
 py7zr; python_version > '3.8'            # License: GNU Lesser General  Public License v2 or later (LGPLv2+) (LGPL-2.1-or-later)
-dohq-artifactory                         # License: MIT License (MIT License)
 pre-commit                               # License: MIT License (MIT)