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ajbairdStevenAWhite
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abaird-genstates: everything should be finalized for production now
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2 files changed

+14
-16
lines changed

2 files changed

+14
-16
lines changed

projects/biogears/libBiogears/src/engine/Systems/BloodChemistry.cpp

Lines changed: 1 addition & 1 deletion
Original file line numberDiff line numberDiff line change
@@ -1194,7 +1194,7 @@ void BloodChemistry::InflammatoryResponse()
11941194
//Burns inflammation happens on a differnt time scale. These parameters were tuned for infecton--return to nominal values
11951195
kDTR = 11.0 * burnTotalBodySurfaceArea; //We assume that larger burns inflict damage more rapidly
11961196
kTr = 0.45 / burnTotalBodySurfaceArea; //We assume that larger burns take longer for trauma to resolve
1197-
tiMin = 0.01; //Promotes faster damage accumulation
1197+
tiMin = 0.008; //Promotes faster damage accumulation
11981198
kD6 = 0.3, xD6 = 0.25, kD = 0.1, kNTNF = 0.2, kN6 = 0.557, hD6 = 4, h66 = 4.0, x1210 = 0.049;
11991199
scale = 1.0;
12001200
}

projects/howto/BurnWoundPainStimulus/src/HowTo-BurnWoundPainStimulus.cpp

Lines changed: 13 additions & 15 deletions
Original file line numberDiff line numberDiff line change
@@ -125,6 +125,8 @@ BurnThread::BurnThread(const std::string logFile, double tbsa)
125125
m_bg->GetEngineTrack()->GetDataRequestManager().CreatePhysiologyDataRequest().Set("MeanUrineOutput", "mL/hr");
126126
m_bg->GetEngineTrack()->GetDataTrack().Probe("totalFluid_mL", m_TotalVolume_mL);
127127
m_bg->GetEngineTrack()->GetDataTrack().Probe("bagVolume_mL", m_ivBagVolume_mL);
128+
m_bg->GetEngineTrack()->GetDataTrack().Probe("totalFluidAlbumin_mL", m_TotalVolumeAlbumin_mL);
129+
m_bg->GetEngineTrack()->GetDataTrack().Probe("bagVolumeAlbumin_mL", m_ivBagVolumeAlbumin_mL);
128130

129131
//Load substances and compounds
130132
SESubstanceCompound* ringers = m_bg->GetSubstanceManager().GetCompound("RingersLactate");
@@ -296,7 +298,7 @@ void BurnThread::FluidLoading(double tbsa)
296298
//compute urine production and max fluid requirements, per parkland formula
297299
const SEPatient& patient = m_bg->GetPatient();
298300
double weight_kg = patient.GetWeight(MassUnit::kg);
299-
double targetLowUrineProduction_mL_Per_Hr = 0.5 * weight_kg;
301+
double targetLowUrineProduction_mL_Per_Hr = 30.0;
300302
double targetHighUrineProduction_mL_Per_Hr = 1.0 * weight_kg; //average of around 50ml/hr
301303
double DayLimit_mL = 4.0 * weight_kg * tbsa;
302304
double initialInfustion_mL_Per_hr = 0.0; //tbsa * 10.0; // Should start at 10*tbsa // (DayLimit_mL / 0.5) / 8.0; //half of the fluid should be loaded in the first 8 hours;
@@ -344,9 +346,11 @@ void BurnThread::FluidLoading(double tbsa)
344346
}
345347

346348
//set fluid to albumin at the 8 hour mark
347-
if ((int)m_bg->GetSimulationTime(TimeUnit::min) == (int)120) {
349+
if ((int)m_bg->GetSimulationTime(TimeUnit::s) == (int)28800) {
348350
fluid = albumin;
349351
m_bg->GetLogger()->Info(asprintf("adding albumin"));
352+
m_bg->GetLogger()->Info(asprintf("Beginning Intervention with infusion at %f %s", initialInfustionAlbumin_mL_Per_hr, "mL_Per_hr"));
353+
SetAlbuminInfusionRate(ringersVolume_mL, initialInfustionAlbumin_mL_Per_hr);
350354
}
351355

352356
//check urine every hour, reset the volume while we are at it
@@ -362,7 +366,7 @@ void BurnThread::FluidLoading(double tbsa)
362366
scaleTitration = errTitrate[errSelection - 1];
363367
//m_bg->GetLogger()->Info(asprintf("Were they right? titrate percent is: %f %s", scaleTitration, "percent"));
364368

365-
if (fluid == ringers && fluidOn == true) {
369+
if (fluidOn == true) {
366370
if (((int)m_bg->GetSimulationTime(TimeUnit::s) + 1) == ((int)hrsBeforeIntervention*3600)) {
367371
double beginningInfusion_mL_Per_hr = 10.0 * tbsa;
368372
m_bg->GetLogger()->Info(asprintf("Beginning Intervention with infusion at %f %s", beginningInfusion_mL_Per_hr, "mL_Per_hr"));
@@ -383,13 +387,13 @@ void BurnThread::FluidLoading(double tbsa)
383387
}
384388
if (fluid == albumin && fluidOn == true) {
385389
if (urineProduction < targetLowUrineProduction_mL_Per_Hr) {
386-
m_bg->GetLogger()->Info(asprintf("Urine production is too low at %f %s", urineProduction, "mL_Per_hr"));
387-
m_albumex->GetRate().SetValue((m_albumex->GetRate().GetValue(VolumePerTimeUnit::mL_Per_hr)) * (1 + titrate) * scaleTitration, VolumePerTimeUnit::mL_Per_hr);
390+
m_bg->GetLogger()->Info(asprintf("Albumin staying at the same rate"));
391+
m_albumex->GetRate().SetValue((m_albumex->GetRate().GetValue(VolumePerTimeUnit::mL_Per_hr)), VolumePerTimeUnit::mL_Per_hr);
388392
m_bg->ProcessAction(*m_albumex);
389393
}
390394
if ((m_bg->GetRenalSystem()->GetMeanUrineOutput(VolumePerTimeUnit::mL_Per_hr) > targetHighUrineProduction_mL_Per_Hr)) {
391-
m_bg->GetLogger()->Info(asprintf("Urine production is too high at %f %s", urineProduction, "mL_Per_hr"));
392-
m_albumex->GetRate().SetValue((m_albumex->GetRate().GetValue(VolumePerTimeUnit::mL_Per_hr)) * (1 - titrate) * scaleTitration, VolumePerTimeUnit::mL_Per_hr);
395+
m_bg->GetLogger()->Info(asprintf("Albumin staying at the same rate"));
396+
m_albumex->GetRate().SetValue((m_albumex->GetRate().GetValue(VolumePerTimeUnit::mL_Per_hr)), VolumePerTimeUnit::mL_Per_hr);
393397
m_bg->ProcessAction(*m_albumex);
394398
}
395399
}
@@ -425,14 +429,12 @@ void BurnThread::FluidLoading(double tbsa)
425429
}
426430
}
427431
// make sure that the bag is full
428-
if (fluid == ringers) {
429432
if (m_ivBagVolume_mL < 1.0) {
430433
m_ringers->GetBagVolume().SetValue(ringersVolume_mL, VolumeUnit::mL);
431434
m_bg->GetLogger()->Info("ringers IV bag is low, refilling bag \n");
432435
m_bg->ProcessAction(*m_ringers);
433436
m_ivBagVolume_mL = ringersVolume_mL; //tracking purposes
434437
}
435-
}
436438

437439
if (fluid == albumin) {
438440
if (m_ivBagVolumeAlbumin_mL < 1.0) {
@@ -462,12 +464,8 @@ void BurnThread::FluidLoading(double tbsa)
462464
}
463465

464466
//advance time
465-
if (fluid == ringers) {
466-
AdvanceTimeFluids();
467-
}
468467

469-
if (fluid == albumin) {
470-
AdvanceTimeFluidsAlbumin();
471-
}
468+
AdvanceTimeFluids();
469+
472470
}
473471
}

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