[Inspiration ](https://external-content.duckduckgo.com/iu/?u=https%3A%2F%2Fmedia.springernature.com%2Flw785%2Fspringer-static%2Fimage%2Fart%253A10.1186%252F1471-2164-6-35%2FMediaObjects%2F12864_2004_Article_236_Fig2_HTML.jpg&f=1&nofb=1&ipt=d1862e9e83269710449d057a213d4b022c241360f79ab50e90343116411254fe&ipo=images)
