diff --git a/requirements.txt b/requirements.txt
index 60e4254..94b0beb 100755
--- a/requirements.txt
+++ b/requirements.txt
@@ -1,11 +1,11 @@
-biopython>=1.78,<2
+biopython>=1.78
 fair-esm==0.4.0
-numpy>=1.16,<1.19
+numpy>=1.16
 pandas>=1.2.3
 pytorch_lightning>=1.3.3
 ray>=1.4.0
 scikit-learn>=0.22.2
-torch>=1.7.0,<1.9
-torchmetrics>=0.3.2,<0.5
+torch>=1.7.0
+torchmetrics>=0.3.2
 tqdm>=4.60.0
-transformers>=4.8,<4.9
+transformers>=4.8