diff --git a/src/napari_deeplabcut/__init__.py b/src/napari_deeplabcut/__init__.py
index 7b49e80..3e34644 100644
--- a/src/napari_deeplabcut/__init__.py
+++ b/src/napari_deeplabcut/__init__.py
@@ -4,6 +4,14 @@
 # FIXME: Circumvent the need to access window.qt_viewer
 warnings.filterwarnings("ignore", category=FutureWarning)
 
+import re
+# Suppress RuntimeWarnings caused by NaN values in dataframe
+# (encountered during model-predicted labels refinement stage)
+warnings.filterwarnings(
+    "ignore",
+    category=RuntimeWarning,
+    message=re.escape("invalid value encountered in cast"),
+)
 
 class VispyWarningFilter(logging.Filter):
     def filter(self, record):