new terms terms describing movement and density of cells

[siiraa]

A new study in the Image Data Resource looking at Cytotoxic T lymphocytes (CTL) in tumors has the following phenotypes that we might want to add new CMPO terms for.

1. increased CTL confinement - this is where the cells move around but don't go very far, so I don't think its quite the same as "decreased cell movement distance", CMPO_0000239
2. enhanced CTL killing - related to "cell killing", http://purl.obolibrary.org/obo/GO_0001906
3. enhanced CTL density
4. transient increase in CTL density

I've already mapped:

1. reduced CTL speed - mapped to "decreased cell movement speed"(CMPO_0000240)
2. enhanced CTL proliferation - mapped to "proliferating cells"
   CMPO_0000241

And I think the final 2 phenotypes are beyond the scope of CMPO

1. reduced tumor growth (could be mapped to
   "decreased tumor growth/size", http://purl.obolibrary.org/obo/MP_0003447
2. vessel normalization

[siiraa]

Simon Jupp added a comment - 25-Apr-17 12:13

CMPO:0000449 - T cell mediated killing against a tumor cell phenotype

[siiraa]

Simon Jupp added a comment - 25-Apr-17 12:20

waiting for more term movement phenotypes - unsure of quality of "cells move around but don't go very far"