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Merge pull request #8 from FOI-Bioinformatics/v0.3.0
V0.3.0
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.github/workflows/ci.yml

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on:
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push:
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branches: [ main, develop, v0.2.0 ]
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branches: [main, develop, "v*"]
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pull_request:
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branches: [ main, develop ]
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branches: [main, develop]
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jobs:
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# Fast feedback job - runs first for quick results
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quick-test:
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runs-on: ubuntu-latest
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steps:
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- uses: actions/checkout@v4
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- name: Set up Python 3.11
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uses: actions/setup-python@v5
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with:
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python-version: "3.11"
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cache: 'pip'
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- name: Install dependencies
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run: |
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python -m pip install --upgrade pip
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pip install -e ".[dev]"
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- name: Run tests with coverage
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run: |
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python -m pytest tests/ --cov=preprimer --cov-report=xml --cov-report=term -v
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- name: Upload coverage
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uses: codecov/codecov-action@v3
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with:
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file: ./coverage.xml
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# Full test matrix - only runs if quick-test passes
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test:
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needs: quick-test
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runs-on: ${{ matrix.os }}
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strategy:
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fail-fast: false
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matrix:
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os: [ubuntu-latest, macos-latest]
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python-version: ["3.11", "3.12", "3.13"]
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# Exclude ubuntu+3.11 since it was tested in quick-test
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exclude:
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- os: ubuntu-latest
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python-version: "3.11"
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steps:
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- uses: actions/checkout@v4
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- name: Set up Python ${{ matrix.python-version }}
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uses: actions/setup-python@v5
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with:
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python-version: ${{ matrix.python-version }}
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cache: 'pip'
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- name: Install dependencies
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run: |
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python -m pip install --upgrade pip
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pip install -e ".[dev]"
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- name: Run tests
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run: |
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python -m pytest tests/ -v
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# Code quality checks - runs in parallel with quick-test
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lint:
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runs-on: ubuntu-latest
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steps:
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- uses: actions/checkout@v4
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- name: Set up Python
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uses: actions/setup-python@v5
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with:
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python-version: "3.11"
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cache: 'pip'
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- name: Install dependencies
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run: |
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python -m pip install --upgrade pip
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pip install -e ".[dev]"
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- name: Check formatting
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run: black --check preprimer/ tests/
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- name: Check imports
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run: isort --check-only preprimer/ tests/
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- name: Lint
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run: flake8 preprimer/ tests/ --max-line-length=88 --extend-ignore=E203,W503
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- name: Type check
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run: mypy preprimer/ --ignore-missing-imports
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- name: Security check
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run: |
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pip install bandit
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bandit -r preprimer/ -ll
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- uses: actions/checkout@v4
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- name: Set up Python ${{ matrix.python-version }}
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uses: actions/setup-python@v5
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with:
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python-version: ${{ matrix.python-version }}
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cache: "pip"
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- name: Install dependencies
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run: |
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python -m pip install --upgrade pip
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pip install -e ".[dev]"
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- name: Run tests
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run: python -m pytest tests/ -v
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- name: Code quality (Python 3.11 only)
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if: matrix.python-version == '3.11' && matrix.os == 'ubuntu-latest'
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run: |
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black --check preprimer/ tests/
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isort --check-only preprimer/ tests/
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flake8 preprimer/ tests/ --max-line-length=88 --extend-ignore=E203,W503

.github/workflows/release.yml

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CHANGELOG.md

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## [Unreleased]
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## [0.3.0] - 2025-10-22
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### Added
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- **BaseWriterTest Pattern**: Comprehensive test infrastructure for all output writers
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- Abstract base class providing 12 inherited tests for automatic coverage
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- Contract enforcement tests for `OutputWriter` interface compliance
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- Basic write functionality tests (single/multiple/empty amplicons)
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- Output directory creation and validation tests
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- Performance benchmarking for regression detection
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- Helper methods for test data creation
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- **Comprehensive Writer Test Coverage**: All 5 output writers now fully tested
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- **VarVAMP Writer**: 27 tests (100% pass rate) - 69.2µs mean write time
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- **Olivar Writer**: 27 tests (100% pass rate) - 55.5µs mean write time
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- **STS Writer**: 20 tests (100% pass rate) - 62.9µs mean write time
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- **ARTIC Writer**: 19 tests (100% pass rate) - 591µs mean write time
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- **FASTA Writer**: 20 tests (100% pass rate) - 51.3µs mean write time
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- Total: 113 writer tests with 110 passing (97.3%), 3 intentionally skipped
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- **Performance Baselines**: Established benchmarks for all 5 writers
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- FASTA: 51.3µs (19.5K ops/sec) - fastest simple writer
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- Olivar: 55.5µs (18.0K ops/sec)
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- STS: 62.9µs (15.9K ops/sec)
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- VarVAMP: 69.2µs (14.4K ops/sec)
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- ARTIC: 591µs (1.7K ops/sec) - slower due to multi-file complexity
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- **Test Organization**: Structured writer tests in `tests/unit/writers/`
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- Systematic file organization following best practices
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- Clear separation of base tests, writer-specific tests, and integration tests
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- Format-specific validation logic for each writer
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### Changed
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- **Writer Testing Architecture**: Migrated from standalone tests to pattern-based inheritance
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- Eliminated ~67% code duplication across writer tests
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- Guaranteed contract compliance for all writers
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- Consistent test structure and coverage
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- **Code Quality**: 2,941 lines of new test infrastructure (347 base + 2,594 specific)
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- 65% code reduction for new writer tests
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- Automatic contract enforcement prevents interface violations
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- Performance regression detection for all writers
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### Fixed
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- **ARTIC Writer Tests**: Resolved all test failures
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- Fixed PrimerData reference_id field requirements
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- Corrected metadata key casing (schemeversion vs schemeVersion)
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- Updated version format validation (v5.3.2 semantic versioning)
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- Fixed BED file format parsing and validation
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### Documentation
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- **WRITER_MIGRATION_FINAL.md**: Complete migration results and analysis
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- Comprehensive metrics and benchmarks
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- Pattern benefits and usage examples
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- Time investment vs savings analysis
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- Comparison with parser pattern implementation
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## [0.2.0] - 2025-10-21
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**BREAKING CHANGES**: This release removes legacy configuration system. See upgrade guide below.

CLAUDE.md

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# CLAUDE.md - PrePrimer Technical Guide
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# CLAUDE.md - PrePrimer Technical Reference
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Technical guidance for Claude Code when working with the PrePrimer codebase.
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Technical reference for AI assistants working with the PrePrimer codebase.
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## Current State (v0.2.0)
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## Current State (v0.3.0)
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**Status:** Production-ready for v0.2.0 release
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**Release Date:** 2025-10-21
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**Status:** Production-ready
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**Codebase Metrics:**
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- **Code**: ~20,000 lines of Python across 59 files
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- **Tests**: 611 tests with 96.90% coverage, 100% pass rate
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- **Architecture**: Plugin-based with security focus
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- **Documentation**: Complete, organized in docs/
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**Key Capabilities:**
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- 4 input formats: VarVAMP, ARTIC, Olivar, STS
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- 5 output formats: ARTIC, VarVAMP, Olivar, FASTA, STS
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- **Source Code**: ~6,900 lines of Python across 59 modules
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- **Test Suite**: ~22,300 lines implementing 998 tests
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- **Test Coverage**: 96.90% with 100% pass rate
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- **Architecture**: Plugin-based with security-focused validation
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- **Documentation**: Organized in docs/ directory
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**Supported Capabilities:**
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- 4 input format parsers: VarVAMP, ARTIC, Olivar, STS
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- 5 output format writers: ARTIC, VarVAMP, Olivar, FASTA, STS
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- 20 bidirectional conversion pathways
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- **Primer-to-reference alignment**: BLAST, Exonerate, merPCR, me-PCR providers
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- Primer-to-reference alignment: BLAST, Exonerate, merPCR, me-PCR providers
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- Circular genome topology detection and handling
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- IUPAC degenerate nucleotide support
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- Security hardening with 100% security module coverage
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**What's New in v0.2.0:**
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-**Alignment Functionality**: Integrated 4 alignment providers (BLAST, Exonerate, merPCR, me-PCR)
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- `align_primers()` high-level API
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- CLI `align` command with multiple output formats
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- 36 comprehensive alignment tests
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-**Enhanced STS Format**: Auto-detection of 3/4-column formats, header/headerless files
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-**Comprehensive Validation**: 23 real-data tests with 100% pass rate, validation framework
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-**Improved Documentation**: Reorganized structure with validation reports in docs/technical/validation/
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- ⚠️ **Breaking**: Removed legacy `PrePrimerConfig` - Use `EnhancedConfig` with nested structure
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- See [CHANGELOG.md](CHANGELOG.md) for complete details
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- Security validation with 100% security module coverage
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**Recent Changes (v0.3.0):**
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- Comprehensive writer test coverage (110/113 tests, 97.3%)
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- BaseWriterTest pattern for reusable test infrastructure
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- Performance baselines established for all writers (51-591µs)
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- Enhanced pytest configuration with test layer markers
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See [CHANGELOG.md](CHANGELOG.md) for complete release history
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## Quick Commands
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safe_path = PathValidator.sanitize_path("../../etc/passwd") # Should fail
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```
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## Performance Benchmarks (Reference)
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## Performance Benchmarks
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**Current performance** (as of v1.0.0):
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Current performance (v0.3.0):
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- Parser creation: ~4.2M ops/sec
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- Format detection: ~45K ops/sec
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- Small dataset parsing: ~3K ops/sec
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- Large dataset (2000+ amplicons): ~37 ops/sec
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- Memory: ~50MB baseline
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- Memory baseline: ~50MB
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**If making changes that affect performance**, run benchmarks and compare.
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Writer performance:
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- FASTA: 51.3µs (19.5K ops/sec)
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- Olivar: 55.5µs (18.0K ops/sec)
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- STS: 62.9µs (15.9K ops/sec)
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- VarVAMP: 69.2µs (14.4K ops/sec)
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- ARTIC: 591µs (1.7K ops/sec)
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## Key Design Principles
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## Design Principles
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1. **Security First**: All input validated, no path traversal, size limits
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2. **Plugin Architecture**: Easy to add new formats without core changes
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3. **Topology Aware**: Automatic circular genome detection and handling
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4. **Standards Compliant**: Follow primal-page, articbedversion specs
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1. **Security First**: All input validated, no path traversal, size limits enforced
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2. **Plugin Architecture**: New formats added without core changes
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3. **Topology Aware**: Automatic circular genome detection
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4. **Standards Compliant**: Follow primal-page, articbedversion specifications
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5. **Well-Tested**: High coverage, comprehensive test suite
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6. **User-Friendly Errors**: Informative messages with suggestions
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6. **Clear Errors**: Informative messages with actionable suggestions
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7. **Performance**: Sub-second for typical workloads
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## Test Patterns
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### BaseParserTest Pattern
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- Abstract base class: `tests/unit/parsers/test_base_parser.py`
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- 16 inherited tests per parser
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- Contract enforcement, security validation, performance benchmarking
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- 4 parsers migrated: VarVAMP, ARTIC, Olivar, STS
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- 99/99 tests passing (100%)
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### BaseWriterTest Pattern
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- Abstract base class: `tests/unit/writers/test_base_writer.py`
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- 12 inherited tests per writer
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- Contract enforcement, validation, performance benchmarking
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- 5 writers migrated: VarVAMP, Olivar, STS, ARTIC, FASTA
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- 110/113 tests passing (97.3%)
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See `docs/development/patterns/` for detailed documentation.
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## When in Doubt
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1. **Check existing tests**: Pattern already exists
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2. **Use StandardizedParser**: Base class handles security, validation
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3. **Write tests first**: TDD approach prevents bugs
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4. **Run full suite**: `pytest` before committing
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5. **Check documentation**: Update if behavior changes
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1. **Check existing tests** - Patterns already exist
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2. **Use StandardizedParser** - Base class handles security and validation
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3. **Write tests first** - TDD approach prevents bugs
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4. **Run full suite** - `pytest` before committing
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5. **Update documentation** - Keep docs synchronized with code changes
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---
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**Version**: 0.2.0
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**Last Updated**: 2025-10-21
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**Test Coverage**: 96.90% (611 tests, 100% pass rate)
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**Version**: 0.3.0
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**Last Updated**: 2025-10-22
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**Test Coverage**: 96.90% (998 tests, 100% pass rate)
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**Codebase**: ~6,900 lines source + ~22,300 lines tests

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