diff --git a/pyproject.toml b/pyproject.toml
index 0a9226b..1d57168 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -25,11 +25,9 @@ description = "Common Operation on Lots of Sequences Tool"
 license = {file = "LICENSE"}
 dependencies = [
     "asyncpg",
-    "aiofiles",
     "boto3",
     "agct >= 0.1.0-dev1",
     "polars ~= 1.0",
-    "hgvs",
     "biocommons.seqrepo",
     "pydantic >=2.0,<3.0",
     "ga4gh.vrs >=2.1.3,<3.0",