update DESCRIPTION

Author: jleechung

DESCRIPTION

@@ -1,6 +1,6 @@
 Package: proActiv
 Title: Estimate Promoter Activity from RNA-Seq data
-Version: 0.99.1
+Version: 0.99.2
 Authors@R: c(
     person(given = "Deniz",
            family = "Demircioglu",
@@ -15,11 +15,17 @@ Authors@R: c(
            family = "Lee",
            role = c("cre"),
            email = "joseph.lee@u.nus.edu"))
-Description: Estimate promoter activity using RNA-Seq data. 
-  This package uses BAM files or junction files from Tophat2
-  or STAR and estimates promoter activity. The promoters of each 
-  gene can be identified by providing a txdb object for the input 
-  annotation version. 
+Description: Most human genes have multiple promoters that control the 
+  expression of different isoforms. The use of these alternative promoters 
+  enables the regulation of isoform expression pre-transcriptionally. 
+  Alternative promoters have been found to be important in a wide number of cell
+  types and diseases. proActiv is an R package that enables the analysis of 
+  promoters from RNA-seq data. proActiv uses aligned reads as input, and 
+  generates counts and normalized promoter activity estimates for each annotated
+  promoter. In particular, proActiv accepts junction files from TopHat2 or STAR 
+  or BAM files as inputs. These estimates can then be used to identify which 
+  promoter is active, which promoter is inactive, and which promoters change 
+  their activity across conditions. 
 License: MIT + file LICENSE
 Encoding: UTF-8
 LazyData: true