diff --git a/secret-manager/regional_samples/createRegionalSecretWithDelayedDestroy.js b/secret-manager/regional_samples/createRegionalSecretWithDelayedDestroy.js
new file mode 100644
index 0000000000..7044f45274
--- /dev/null
+++ b/secret-manager/regional_samples/createRegionalSecretWithDelayedDestroy.js
@@ -0,0 +1,57 @@
+// Copyright 2025 Google LLC
+//
+// Licensed under the Apache License, Version 2.0 (the "License");
+// you may not use this file except in compliance with the License.
+// You may obtain a copy of the License at
+//
+//     https://www.apache.org/licenses/LICENSE-2.0
+//
+// Unless required by applicable law or agreed to in writing, software
+// distributed under the License is distributed on an "AS IS" BASIS,
+// WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+// See the License for the specific language governing permissions and
+// limitations under the License.
+
+'use strict';
+
+async function main(projectId, locationId, secretId, timeToLive) {
+  // [START secretmanager_create_regional_secret_with_delayed_destroy]
+  /**
+   * TODO(developer): Uncomment these variables before running the sample.
+   */
+  // const project = 'my-project';
+  // const locationId = 'my-location';
+  // const secretId = 'my-secret';
+  // const timeToLive = 86400;
+  const parent = `projects/${projectId}/locations/${locationId}`;
+
+  // Imports the Secret Manager library
+  const {SecretManagerServiceClient} = require('@google-cloud/secret-manager');
+
+  // Adding the endpoint to call the regional secret manager server
+  const options = {};
+  options.apiEndpoint = `secretmanager.${locationId}.rep.googleapis.com`;
+
+  // Instantiates a client
+  const client = new SecretManagerServiceClient(options);
+
+  async function createRegionalSecretWithDelayedDestroy() {
+    const [secret] = await client.createSecret({
+      parent: parent,
+      secretId: secretId,
+      secret: {
+        version_destroy_ttl: {
+          seconds: timeToLive,
+        },
+      },
+    });
+
+    console.log(`Created regional secret ${secret.name}`);
+  }
+
+  createRegionalSecretWithDelayedDestroy();
+  // [END secretmanager_create_regional_secret_with_delayed_destroy]
+}
+
+const args = process.argv.slice(2);
+main(...args).catch(console.error);
diff --git a/secret-manager/regional_samples/disableRegionalSecretDelayedDestroy.js b/secret-manager/regional_samples/disableRegionalSecretDelayedDestroy.js
new file mode 100644
index 0000000000..b94fdaa308
--- /dev/null
+++ b/secret-manager/regional_samples/disableRegionalSecretDelayedDestroy.js
@@ -0,0 +1,55 @@
+// Copyright 2025 Google LLC
+//
+// Licensed under the Apache License, Version 2.0 (the "License");
+// you may not use this file except in compliance with the License.
+// You may obtain a copy of the License at
+//
+//     https://www.apache.org/licenses/LICENSE-2.0
+//
+// Unless required by applicable law or agreed to in writing, software
+// distributed under the License is distributed on an "AS IS" BASIS,
+// WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+// See the License for the specific language governing permissions and
+// limitations under the License.
+
+'use strict';
+
+async function main(projectId, locationId, secretId) {
+  // [START secretmanager_disable_regional_secret_delayed_destroy]
+  /**
+   * TODO(developer): Uncomment these variables before running the sample.
+   */
+  // const projectId = 'my-project';
+  // const locationId = 'my-location';
+  // const secretId = 'my-secret';
+  const name = `projects/${projectId}/locations/${locationId}/secrets/${secretId}`;
+
+  // Imports the Secret Manager library
+  const {SecretManagerServiceClient} = require('@google-cloud/secret-manager');
+
+  // Adding the endpoint to call the regional secret manager server
+  const options = {};
+  options.apiEndpoint = `secretmanager.${locationId}.rep.googleapis.com`;
+
+  // Instantiates a client
+  const client = new SecretManagerServiceClient(options);
+
+  async function disableRegionalSecretDelayedDestroy() {
+    const [secret] = await client.updateSecret({
+      secret: {
+        name: name,
+      },
+      updateMask: {
+        paths: ['version_destroy_ttl'],
+      },
+    });
+
+    console.info(`Disabled delayed destroy ${secret.name}`);
+  }
+
+  disableRegionalSecretDelayedDestroy();
+  // [END secretmanager_disable_regional_secret_delayed_destroy]
+}
+
+const args = process.argv.slice(2);
+main(...args).catch(console.error);
diff --git a/secret-manager/regional_samples/updateRegionalSecretWithDelayedDestroy.js b/secret-manager/regional_samples/updateRegionalSecretWithDelayedDestroy.js
new file mode 100644
index 0000000000..50917293c4
--- /dev/null
+++ b/secret-manager/regional_samples/updateRegionalSecretWithDelayedDestroy.js
@@ -0,0 +1,59 @@
+// Copyright 2025 Google LLC
+//
+// Licensed under the Apache License, Version 2.0 (the "License");
+// you may not use this file except in compliance with the License.
+// You may obtain a copy of the License at
+//
+//     https://www.apache.org/licenses/LICENSE-2.0
+//
+// Unless required by applicable law or agreed to in writing, software
+// distributed under the License is distributed on an "AS IS" BASIS,
+// WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+// See the License for the specific language governing permissions and
+// limitations under the License.
+
+'use strict';
+
+async function main(projectId, locationId, secretId, updatedTimeToLive) {
+  // [START secretmanager_update_regional_secret_with_delayed_destroy]
+  /**
+   * TODO(developer): Uncomment these variables before running the sample.
+   */
+  // const projectId = 'my-project';
+  // const locationId = 'my-location';
+  // const secretId = 'my-secret';
+  // const updatedTimeToLive = 86400;
+  const name = `projects/${projectId}/locations/${locationId}/secrets/${secretId}`;
+
+  // Imports the Secret Manager library
+  const {SecretManagerServiceClient} = require('@google-cloud/secret-manager');
+
+  // Adding the endpoint to call the regional secret manager server
+  const options = {};
+  options.apiEndpoint = `secretmanager.${locationId}.rep.googleapis.com`;
+
+  // Instantiates a client
+  const client = new SecretManagerServiceClient(options);
+
+  async function updateRegionalSecret() {
+    const [secret] = await client.updateSecret({
+      secret: {
+        name: name,
+        version_destroy_ttl: {
+          seconds: updatedTimeToLive,
+        },
+      },
+      updateMask: {
+        paths: ['version_destroy_ttl'],
+      },
+    });
+
+    console.info(`Updated regional secret ${secret.name}`);
+  }
+
+  updateRegionalSecret();
+  // [END secretmanager_update_regional_secret_with_delayed_destroy]
+}
+
+const args = process.argv.slice(2);
+main(...args).catch(console.error);
diff --git a/secret-manager/test/secretmanager.test.js b/secret-manager/test/secretmanager.test.js
index 8d169b59d6..145f27ccb5 100644
--- a/secret-manager/test/secretmanager.test.js
+++ b/secret-manager/test/secretmanager.test.js
@@ -599,4 +599,54 @@ describe('Secret Manager samples', () => {
       name: `${secret.name}-delayedDestroy`,
     });
   });
+
+  it('creates a regional secret with delayed destroy', async () => {
+    const timeToLive = 24 * 60 * 60;
+    const output = execSync(
+      `node regional_samples/createRegionalSecretWithDelayedDestroy.js ${projectId} ${locationId} ${secretId}-2-dd ${timeToLive}`
+    );
+    assert.match(output, new RegExp('Created regional secret'));
+  });
+
+  it('disables a regional secret delayed destroy', async () => {
+    await regionalClient.createSecret({
+      parent: `projects/${projectId}/locations/${locationId}`,
+      secretId: `${secretId}-delayedDestroy`,
+      secret: {
+        version_destroy_ttl: {
+          seconds: 24 * 60 * 60,
+        },
+      },
+    });
+
+    const output = execSync(
+      `node regional_samples/disableRegionalSecretDelayedDestroy.js ${projectId} ${locationId} ${secretId}-delayedDestroy`
+    );
+    assert.match(output, new RegExp('Disabled delayed destroy'));
+
+    await regionalClient.deleteSecret({
+      name: `projects/${projectId}/locations/${locationId}/secrets/${secretId}-delayedDestroy`,
+    });
+  });
+
+  it('updates a regional secret delayed destroy', async () => {
+    const updatedTimeToLive = 24 * 60 * 60 * 2;
+    await regionalClient.createSecret({
+      parent: `projects/${projectId}/locations/${locationId}`,
+      secretId: `${secretId}-delayedDestroy`,
+      secret: {
+        version_destroy_ttl: {
+          seconds: 24 * 60 * 60,
+        },
+      },
+    });
+
+    const output = execSync(
+      `node regional_samples/updateRegionalSecretWithDelayedDestroy.js ${projectId} ${locationId} ${secretId}-delayedDestroy ${updatedTimeToLive}`
+    );
+    assert.match(output, new RegExp('Updated regional secret'));
+    await regionalClient.deleteSecret({
+      name: `projects/${projectId}/locations/${locationId}/secrets/${secretId}-delayedDestroy`,
+    });
+  });
 });