Peak2Gene heatmap with unbalanced groups #1585
Unanswered
benayang
asked this question in
Questions / Documentation
Replies: 0 comments
Sign up for free
to join this conversation on GitHub.
Already have an account?
Sign in to comment
Uh oh!
There was an error while loading. Please reload this page.
-
Hello,
I have integrated data across 2 time points (Young and Aged) and have isolated a cell type cluster of interest as a separate ArchR project using subsetArchRProject. I've added Peak2Gene linkages and am interested in identifying age-specific linkages using plotPeak2GeneHeatmap with age as the "groupBy" paramter. The two time points are imbalanced (Young -- 402, Aged -- 178) and the resulting heatmap only shows results for the Young time point. Loading the seATAC-Group-KNN.rds object and tabulating the number of Young and Aged cells per KNN grouping shows a strong bias towards Young cells (shown below). Is there a way to make the groupings more even so linkages are provided for both Young and Aged?
Beta Was this translation helpful? Give feedback.
All reactions