T2T Genome

[fansalon]

Hi there,

I am using ArchR to analyse some data which have been mapped to the recently generated T2T human assembly. Of course, when I try to specify addArchRGenome("T2T") I got an error reporting that this genome version is not currently supported by ArchR.

I tried to generate the annotations by myself and I am able to generate the T2T version of the BSgenome to be used as argument of the createGenomeAnnotation() function as well as the TxDb to be used in createGeneAnnotation(). However, I fail in generating the OrgDB object to be used in createGeneAnnotation() (I tried with the makeOrgPackageFromNCBI()).

After having tried different workarounds I am still not able to get rid of this. So I was thinking, are you perhaps planning to support soon the T2T genome version too?

Thanks.
Federico