Reference-informed addGeneScoreMatrix() #2177
danieljrichard
started this conversation in
General
Replies: 0 comments
Sign up for free
to join this conversation on GitHub.
Already have an account?
Sign in to comment
Uh oh!
There was an error while loading. Please reload this page.
-
Hello - I'm really interested in using ArchR to analyze a Multiome dataset I've generated. In addition to general biological insights, I wanted to use the Multiome dataset as a 'reference' to better inform ATAC --> gene expression inference from some scATAC datasets I have from the same tissue.
Is there any way to use the information from an ArchR integrated analysis (e.g. the peak-to-gene links) to inform the genescore inferrence? I also imagine this'd be useful to do in a cell-type-specific way, as one could imagine different regulatory relationships at play in different trans environments.
Any help/advice would be greatly appreciated!
Beta Was this translation helpful? Give feedback.
All reactions