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docs/index.md

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## Panoptic Segmentation Features 🌟
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- Fast WSI-level panoptic segmentation. See [example](https://hautaniemilab.github.io/histolytics/user_guide/seg/panoptic_segmentation/).
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- Fast WSI-level panoptic segmentation. See [example](./user_guide/seg/panoptic_segmentation/).
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- Low memory-footprint segmentation results with [`__geo_interface__`](https://gist.github.com/sgillies/2217756)-specification.
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- Multiple vectorized segmentation output formats (geojson/feather/parquet).
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- Several panoptic segmentation model architectures for histological WSIs with flexible backbone support: See [example](https://hautaniemilab.github.io/histolytics/user_guide/seg/backbones/)
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- Several panoptic segmentation model architectures for histological WSIs with flexible backbone support: See [example](./user_guide/seg/backbones/)
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- Pre-trained models in model-hub. See: [histolytics-hub](https://huggingface.co/histolytics-hub)
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## Spatial Analysis Features 📊
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- Fast Spatial Querying of WSI-scale panoptic segmentation maps. See [example](https://hautaniemilab.github.io/histolytics/user_guide/spatial/querying/)
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- Spatial indexing/partitioning for localized spatial statistics and analysis. See [example](https://hautaniemilab.github.io/histolytics/user_guide/spatial/partitioning/)
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- Graph-based neighborhood analysis for local cell neighborhoods. See [example](https://hautaniemilab.github.io/histolytics/user_guide/spatial/nhoods/)
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- Plotting utilities for spatial data visualization. See [example](https://hautaniemilab.github.io/histolytics/user_guide/spatial/legendgram/)
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- Spatial clustering and cluster centrography metrics. See [example](https://hautaniemilab.github.io/histolytics/user_guide/spatial/clustering/)
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- Large set of morphological, intensity, chromatin distribution, and textural features at nuclear level. See [example](https://hautaniemilab.github.io/histolytics/user_guide/spatial/nuclear_features/)
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- Large set of collagen fiber and intensity based features to characterize stroma and ECM. See [example](https://hautaniemilab.github.io/histolytics/user_guide/spatial/stromal_features/)
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- Fast Spatial Querying of WSI-scale panoptic segmentation maps. See [example](./user_guide/spatial/querying/)
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- Spatial indexing/partitioning for localized spatial statistics and analysis. See [example](./user_guide/spatial/partitioning/)
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- Graph-based neighborhood analysis for local cell neighborhoods. See [example](./user_guide/spatial/nhoods/)
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- Plotting utilities for spatial data visualization. See [example](./user_guide/spatial/legendgram/)
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- Spatial clustering and cluster centrography metrics. See [example](./user_guide/spatial/clustering/)
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- Large set of morphological, intensity, chromatin distribution, and textural features at nuclear level. See [example](./user_guide/spatial/nuclear_features/)
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- Large set of collagen fiber and intensity based features to characterize stroma and ECM. See [example](./user_guide/spatial/stromal_features/)
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## Example Workflows 🧪
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#### Immuno-oncology Profiling:
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- [Spatial Statistics of TILs](https://hautaniemilab.github.io/histolytics/user_guide/workflows/TIL_workflow/).
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- [Profiling TLS and Lymphoid Aggregates](https://hautaniemilab.github.io/histolytics/user_guide/workflows/tls_lymphoid_aggregate/).
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- [Spatial Statistics of TILs](./user_guide/workflows/TIL_workflow/).
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- [Profiling TLS and Lymphoid Aggregates](./user_guide/workflows/tls_lymphoid_aggregate/).
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#### Nuclear Pleomorphism:
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- [Nuclear Morphology Analysis](https://hautaniemilab.github.io/histolytics/user_guide/workflows/nuclear_morphology/).
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- [Nuclear Chromatin Distribution Analysis](https://hautaniemilab.github.io/histolytics/user_guide/workflows/chromatin_patterns/).
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- [Nuclear Morphology Analysis](./user_guide/workflows/nuclear_morphology/).
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- [Nuclear Chromatin Distribution Analysis](./user_guide/workflows/chromatin_patterns/).
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#### TME Characterization:
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- [Collagen Fiber Disorder Analysis](https://hautaniemilab.github.io/histolytics/user_guide/workflows/collagen_orientation/).
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- [Characterization of Desmoplastic Stroma](https://hautaniemilab.github.io/histolytics/user_guide/workflows/clustering_desmoplasia/).
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- [Collagen Fiber Disorder Analysis](./user_guide/workflows/collagen_orientation/).
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- [Characterization of Desmoplastic Stroma](./user_guide/workflows/clustering_desmoplasia/).
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#### Nuclei Neighborhoods:
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- [Tumor Cell Accessibility](https://hautaniemilab.github.io/histolytics/user_guide/workflows/tumor_cell_accessibility/).
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- [Tumor Cell Accessibility](./user_guide/workflows/tumor_cell_accessibility/).
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## Installation 🛠️

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