diff --git a/public/locales/en/translation.json b/public/locales/en/translation.json
index 955adcdcd..faebf0018 100644
--- a/public/locales/en/translation.json
+++ b/public/locales/en/translation.json
@@ -338,6 +338,7 @@
         "store": "Filter Store"
     },
     "help": {
+        "advertiseAvxForRosetta": "Enables AVX instruction set support when running Windows games through Rosetta on Apple Silicon Macs. This may be required for some games like Death Stranding that need AVX support.",
         "amdfsr": "AMD's FSR helps boost framerate by upscaling lower resolutions in Fullscreen Mode. Image quality increases from 5 to 1 at the cost of a slight performance hit. Enabling may improve performance.",
         "custom_themes_path": "Do not use CSS files from untrusted sources. When in doubt, ask for a review in our Discord channel.",
         "custom_themes_wiki": "Check the Wiki for more details on adding custom themes. Click here.",
@@ -927,6 +928,7 @@
         "addgamestoapplications": "Add games to Applications automatically",
         "addgamestostartmenu": "Add games to start menu automatically",
         "addgamestosteam": "Add games to Steam automatically",
+        "advertiseAvxForRosetta": "Advertise AVX for Rosetta",
         "autodxvk": "Auto Install/Update DXVK on Prefix",
         "autodxvknvapi": "Auto Install/Update DXVK-NVAPI on Prefix",
         "autoLaunchHyperPlay": "Auto Launch HyperPlay",
diff --git a/src/backend/config.ts b/src/backend/config.ts
index 38d56c08e..ba141af35 100644
--- a/src/backend/config.ts
+++ b/src/backend/config.ts
@@ -286,6 +286,8 @@ class GlobalConfigV0 extends GlobalConfig {
 
     // @ts-expect-error TODO: We need to settle on *one* place to define settings defaults
     return {
+      advertiseAvxForRosetta:
+        isMac && (defaultWine as WineInstallation)?.type === 'toolkit',
       checkUpdatesInterval: 10,
       enableUpdates: false,
       addDesktopShortcuts: false,
diff --git a/src/backend/game_config.ts b/src/backend/game_config.ts
index 4f33820e4..c56c83afb 100644
--- a/src/backend/game_config.ts
+++ b/src/backend/game_config.ts
@@ -206,6 +206,7 @@ class GameConfigV0 extends GameConfig {
     // The settings defined work as overrides.
 
     const {
+      advertiseAvxForRosetta,
       autoInstallDxvk,
       autoInstallVkd3d,
       preferSystemLibs,
@@ -236,6 +237,7 @@ class GameConfigV0 extends GameConfig {
     const defaultSettings = {
       autoInstallDxvk,
       autoInstallVkd3d,
+      advertiseAvxForRosetta,
       preferSystemLibs,
       autoSyncSaves,
       enableEsync,
@@ -288,8 +290,8 @@ class GameConfigV0 extends GameConfig {
     }
   }
 
-  public setSetting(key: string, value: unknown) {
-    this.config[key] = value
+  public setSetting(key: keyof GameSettings, value: unknown) {
+    this.config[key] = value as never
     logInfo(`${this.appName}: Setting ${key} to ${JSON.stringify(value)}`)
     return this.flush()
   }
diff --git a/src/backend/launcher.ts b/src/backend/launcher.ts
index 069778cd7..fbad97bcc 100644
--- a/src/backend/launcher.ts
+++ b/src/backend/launcher.ts
@@ -464,6 +464,12 @@ function setupWineEnvVars(
       )
     }
   }
+
+  // Set Rosetta AVX setting for macOS
+  if (isMac && gameSettings.advertiseAvxForRosetta) {
+    ret.ROSETTA_ADVERTISE_AVX = '1'
+  }
+
   return ret
 }
 
diff --git a/src/common/types.ts b/src/common/types.ts
index f1e535b31..a72241a7a 100644
--- a/src/common/types.ts
+++ b/src/common/types.ts
@@ -191,6 +191,7 @@ export interface GameInfo {
 }
 
 export interface GameSettings {
+  advertiseAvxForRosetta: boolean
   autoInstallDxvk: boolean
   autoInstallVkd3d: boolean
   autoInstallDxvkNvapi: boolean
diff --git a/src/frontend/screens/Settings/components/AdvertiseAvxForRosetta.tsx b/src/frontend/screens/Settings/components/AdvertiseAvxForRosetta.tsx
new file mode 100644
index 000000000..2aba47529
--- /dev/null
+++ b/src/frontend/screens/Settings/components/AdvertiseAvxForRosetta.tsx
@@ -0,0 +1,48 @@
+import ContextProvider from 'frontend/state/ContextProvider'
+import React, { useContext } from 'react'
+import { useTranslation } from 'react-i18next'
+import SettingsContext from '../SettingsContext'
+import useSetting from 'frontend/hooks/useSetting'
+import { ToggleSwitch } from 'frontend/components/UI'
+import { FontAwesomeIcon } from '@fortawesome/react-fontawesome'
+import { faCircleInfo } from '@fortawesome/free-solid-svg-icons'
+import { defaultWineVersion } from '..'
+
+const AdvertiseAvxForRosetta = () => {
+  const { t } = useTranslation()
+  const { platform } = useContext(ContextProvider)
+  const { isMacNative } = useContext(SettingsContext)
+  const isMac = platform === 'darwin'
+  const [wineVersion] = useSetting('wineVersion', defaultWineVersion)
+  const [advertiseAvxForRosetta, setAdvertiseAvxForRosetta] = useSetting(
+    'advertiseAvxForRosetta',
+    false
+  )
+
+  // Only show on macOS when using toolkit wine and not native games
+  if (!isMac || isMacNative || wineVersion.type !== 'toolkit') {
+    return <></>
+  }
+
+  return (
+    <div className="toggleRow">
+      <ToggleSwitch
+        htmlId="advertiseAvxForRosettaToggle"
+        value={advertiseAvxForRosetta || false}
+        handleChange={() => setAdvertiseAvxForRosetta(!advertiseAvxForRosetta)}
+        title={t('setting.advertiseAvxForRosetta', 'Advertise AVX for Rosetta')}
+      />
+
+      <FontAwesomeIcon
+        className="helpIcon"
+        icon={faCircleInfo}
+        title={t(
+          'help.advertiseAvxForRosetta',
+          'Enables AVX instruction set support when running Windows games through Rosetta on Apple Silicon Macs. This may be required for some games like Death Stranding that need AVX support.'
+        )}
+      />
+    </div>
+  )
+}
+
+export default AdvertiseAvxForRosetta
diff --git a/src/frontend/screens/Settings/components/index.ts b/src/frontend/screens/Settings/components/index.ts
index b241c2990..a4790c80b 100644
--- a/src/frontend/screens/Settings/components/index.ts
+++ b/src/frontend/screens/Settings/components/index.ts
@@ -1,4 +1,5 @@
 export { default as AlternativeExe } from './AlternativeExe'
+export { default as AdvertiseAvxForRosetta } from './AdvertiseAvxForRosetta'
 export { default as AutoDXVK } from './AutoDXVK'
 export { default as AutoDXVKNVAPI } from './AutoDXVKNVAPI'
 export { default as AutoUpdateGames } from './AutoUpdateGames'
diff --git a/src/frontend/screens/Settings/sections/GamesSettings/index.tsx b/src/frontend/screens/Settings/sections/GamesSettings/index.tsx
index f23070b53..6b4465e11 100644
--- a/src/frontend/screens/Settings/sections/GamesSettings/index.tsx
+++ b/src/frontend/screens/Settings/sections/GamesSettings/index.tsx
@@ -5,6 +5,7 @@ import React, { useContext, useState, useEffect } from 'react'
 import { useTranslation } from 'react-i18next'
 import {
   AlternativeExe,
+  AdvertiseAvxForRosetta,
   AutoDXVK,
   AutoDXVKNVAPI,
   AutoVKD3D,
@@ -115,6 +116,7 @@ export default function GamesSettings() {
             {!isCrossover && (
               <>
                 <AutoDXVK />
+                <AdvertiseAvxForRosetta />
                 {isLinux && (
                   <>
                     <AutoDXVKNVAPI />