diff --git a/.github/workflows/build-test-publish.yml b/.github/workflows/build-test-publish.yml
index f2c5acd67..443af853b 100644
--- a/.github/workflows/build-test-publish.yml
+++ b/.github/workflows/build-test-publish.yml
@@ -89,8 +89,8 @@ jobs:
           file(TO_CMAKE_PATH "\$ENV{GITHUB_WORKSPACE}/../../Ex" CTEST_SOURCE_DIRECTORY)
           file(TO_CMAKE_PATH "\$ENV{GITHUB_WORKSPACE}/../../bld/" CTEST_BINARY_DIRECTORY)
           set(dashboard_source_name "${GITHUB_REPOSITORY}")
-          if(ENV{GITHUB_REF} MATCHES "master")
-            set(branch "-master")
+          if(ENV{GITHUB_REF} MATCHES "main")
+            set(branch "-main")
             set(dashboard_model "Continuous")
           else()
             set(branch "-${GITHUB_REF}")
@@ -183,8 +183,8 @@ jobs:
           file(TO_CMAKE_PATH "\$ENV{GITHUB_WORKSPACE}/../../Ex" CTEST_SOURCE_DIRECTORY)
           file(TO_CMAKE_PATH "\$ENV{GITHUB_WORKSPACE}/../../bld/" CTEST_BINARY_DIRECTORY)
           set(dashboard_superbuild 1)
-          if(ENV{GITHUB_REF} MATCHES "master")
-            set(branch "-master")
+          if(ENV{GITHUB_REF} MATCHES "main")
+            set(branch "-main")
             set(dashboard_model "Continuous")
           else()
             set(branch "-${GITHUB_REF}")
@@ -322,8 +322,8 @@ jobs:
           file(TO_CMAKE_PATH "\$ENV{GITHUB_WORKSPACE}/../../Ex" CTEST_SOURCE_DIRECTORY)
           file(TO_CMAKE_PATH "\$ENV{GITHUB_WORKSPACE}/../../bld/" CTEST_BINARY_DIRECTORY)
           set(dashboard_superbuild 1)
-          if(ENV{GITHUB_REF} MATCHES "master")
-            set(branch "-master")
+          if(ENV{GITHUB_REF} MATCHES "main")
+            set(branch "-main")
             set(dashboard_model "Continuous")
           else()
             set(branch "-${GITHUB_REF}")
@@ -382,7 +382,7 @@ jobs:
         uses: nwtgck/actions-netlify@v3.0.0
         with:
           publish-dir: '${{ github.workspace }}/site'
-          production-branch: master
+          production-branch: main
           production-deploy: true
           github-token: ${{ secrets.GITHUB_TOKEN }}
           deploy-message: ${{ github.event.pull_request.title }})
diff --git a/.github/workflows/lint.yml b/.github/workflows/lint.yml
index ffe248709..4c2d54586 100644
--- a/.github/workflows/lint.yml
+++ b/.github/workflows/lint.yml
@@ -28,5 +28,5 @@ jobs:
         VALIDATE_PYTHON_BLACK: true
         # VALIDATE_YAML: true .clang-format file does not pass validation
         FILTER_REGEX_EXCLUDE: (.github/labeler.yml|.*\.clang-format)
-        DEFAULT_BRANCH: master
+        DEFAULT_BRANCH: main
         GITHUB_TOKEN: ${{ secrets.GITHUB_TOKEN }}
diff --git a/README.rst b/README.rst
index f14ee2204..e3503b201 100644
--- a/README.rst
+++ b/README.rst
@@ -1,11 +1,11 @@
 ITK Sphinx Examples
 ===================
 
-.. image:: https://github.com/InsightSoftwareConsortium/ITKSphinxExamples/workflows/Build,%20test,%20publish/badge.svg?branch=master
-   :target: https://github.com/InsightSoftwareConsortium/ITKSphinxExamples/actions?query=workflow%3A%22Build%2C+test%2C+publish%22+branch%3Amaster
+.. image:: https://github.com/InsightSoftwareConsortium/ITKSphinxExamples/workflows/Build,%20test,%20publish/badge.svg?branch=main
+   :target: https://github.com/InsightSoftwareConsortium/ITKSphinxExamples/actions?query=workflow%3A%22Build%2C+test%2C+publish%22+branch%3Amain
 
 .. image:: https://img.shields.io/badge/License-Apache%202.0-blue.svg?style=shield
-   :target: https://github.com/InsightSoftwareConsortium/ITKSphinxExamples/blob/master/LICENSE
+   :target: https://github.com/InsightSoftwareConsortium/ITKSphinxExamples/blob/main/LICENSE
 
 
 A set of cookbook examples for the Insight Toolkit, ITK_.
diff --git a/Utilities/Dashboard/itkexamples_common.cmake b/Utilities/Dashboard/itkexamples_common.cmake
index 4cff78ded..dd50baa68 100644
--- a/Utilities/Dashboard/itkexamples_common.cmake
+++ b/Utilities/Dashboard/itkexamples_common.cmake
@@ -140,9 +140,9 @@ if(NOT DEFINED dashboard_git_url)
 endif()
 if(NOT DEFINED dashboard_git_branch)
   #if("${dashboard_model}" STREQUAL "Nightly")
-  #  set(dashboard_git_branch nightly-master)
+  #  set(dashboard_git_branch nightly-main)
   #else()
-    set(dashboard_git_branch master)
+    set(dashboard_git_branch main)
   #endif()
 endif()
 if(NOT DEFINED dashboard_git_crlf)
diff --git a/Utilities/GitSetup/git-review-push b/Utilities/GitSetup/git-review-push
index 3530c69fd..81d06c1de 100755
--- a/Utilities/GitSetup/git-review-push
+++ b/Utilities/GitSetup/git-review-push
@@ -55,7 +55,7 @@ test -n "$remote" || remote="origin"
 if test -z "$no_topic"; then
   # Identify and validate the topic branch name.
   topic="$(git symbolic-ref HEAD | sed -e 's|^refs/heads/||')"
-  if test "$topic" = "master"; then
+  if test "$topic" = "main"; then
     die 'Please name your topic:
     git checkout -b descriptive-name'
   fi
@@ -68,11 +68,11 @@ if test -z "$refspecs"; then
   exit 0
 fi
 
-# Fetch the current upstream master branch head.
+# Fetch the current upstream main branch head.
 # This helps the computation of a minimal pack to push.
 if test -z "$upstream_remote"; then
-  echo "Fetching $upstream_remote master"
-  fetch_out=$(git fetch "$upstream_remote" master 2>&1) || die "$fetch_out"
+  echo "Fetching $upstream_remote main"
+  fetch_out=$(git fetch "$upstream_remote" main 2>&1) || die "$fetch_out"
 fi
 
 # Push.  Save output and exit code.
diff --git a/Utilities/GitSetup/setup-git-aliases b/Utilities/GitSetup/setup-git-aliases
index 8dbc13204..e5d976042 100755
--- a/Utilities/GitSetup/setup-git-aliases
+++ b/Utilities/GitSetup/setup-git-aliases
@@ -3,11 +3,11 @@
 # Alias to checkout a pull request by its numerical id
 git config alias.pr "!bash Utilities/GitSetup/git-pr"
 # Remove previously checked out pull request
-git config alias.pr-clean '!git checkout master ; git for-each-ref refs/heads/pr/* --format="%(refname)" | while read ref ; do branch=${ref#refs/heads/} ; git branch -D $branch ; done'
+git config alias.pr-clean '!git checkout main ; git for-each-ref refs/heads/pr/* --format="%(refname)" | while read ref ; do branch=${ref#refs/heads/} ; git branch -D $branch ; done'
 
 # Alias to push the current topic branch to GitHub
 git config alias.review-push "!bash Utilities/GitSetup/git-review-push"
 
 # Useful alias to see what commits are on the current branch with respect to
-# upstream/master
-git config alias.prepush 'log --graph --stat upstream/master..'
+# upstream/main
+git config alias.prepush 'log --graph --stat upstream/main..'
diff --git a/Utilities/SetupForDevelopment.sh b/Utilities/SetupForDevelopment.sh
index 7fe15363e..8bc48fdf5 100755
--- a/Utilities/SetupForDevelopment.sh
+++ b/Utilities/SetupForDevelopment.sh
@@ -28,13 +28,13 @@ Utilities/GitSetup/setup-git-aliases && echo &&
 Utilities/GitSetup/tips &&
 Utilities/GitSetup/github-tips
 
-# Rebase master by default
+# Rebase main by default
 git config rebase.stat true
-git config branch.master.rebase true
+git config branch.main.rebase true
 
-# Rebase master by default
+# Rebase main by default
 git config rebase.stat true
-git config branch.master.rebase true
+git config branch.main.rebase true
 
 # Record the version of this setup so Hooks/pre-commit can check it.
 SetupForDevelopment_VERSION=1
diff --git a/src/Core/Transform/MutualInformationAffine/Documentation.rst b/src/Core/Transform/MutualInformationAffine/Documentation.rst
index c13e4b84d..4728df73e 100644
--- a/src/Core/Transform/MutualInformationAffine/Documentation.rst
+++ b/src/Core/Transform/MutualInformationAffine/Documentation.rst
@@ -51,7 +51,7 @@ Jupyter Notebook
 ----------------
 
 .. image:: https://mybinder.org/badge_logo.svg
-  :target: https://mybinder.org/v2/gh/InsightSoftwareConsortium/ITKSphinxExamples/master?filepath=src%2FCore%2FTransform%2FMutualInformationAffine%2FMutualInformationAffine.ipynb
+  :target: https://mybinder.org/v2/gh/InsightSoftwareConsortium/ITKSphinxExamples/main?filepath=src%2FCore%2FTransform%2FMutualInformationAffine%2FMutualInformationAffine.ipynb
 
 
 Code
diff --git a/src/Filtering/ImageStatistics/CalculateImageMoments/Documentation.rst b/src/Filtering/ImageStatistics/CalculateImageMoments/Documentation.rst
index 733835242..ad1d344ab 100644
--- a/src/Filtering/ImageStatistics/CalculateImageMoments/Documentation.rst
+++ b/src/Filtering/ImageStatistics/CalculateImageMoments/Documentation.rst
@@ -57,7 +57,7 @@ Jupyter Notebook
 -----------------
 
 .. image:: https://mybinder.org/badge_logo.svg
-   :target: https://mybinder.org/v2/gh/InsightSoftwareConsortium/ITKExamples/master?filepath=src%2FFiltering%2FImageStatistics%2FImageMomentsCalculator%2FCalculateEllipseMoments.ipynb
+   :target: https://mybinder.org/v2/gh/InsightSoftwareConsortium/ITKExamples/main?filepath=src%2FFiltering%2FImageStatistics%2FImageMomentsCalculator%2FCalculateEllipseMoments.ipynb
 
 Code
 ----
diff --git a/src/Numerics/Optimizers/ExhaustiveOptimizer/Documentation.rst b/src/Numerics/Optimizers/ExhaustiveOptimizer/Documentation.rst
index 403f6de2a..87f766e0d 100644
--- a/src/Numerics/Optimizers/ExhaustiveOptimizer/Documentation.rst
+++ b/src/Numerics/Optimizers/ExhaustiveOptimizer/Documentation.rst
@@ -30,7 +30,7 @@ Jupyter Notebook
 -----------------
 
 .. image:: https://mybinder.org/badge_logo.svg
- :target: https://mybinder.org/v2/gh/InsightSoftwareConsortium/ITKSphinxExamples/master?filepath=src%2FNumerics%2FOptimizers%2FExhaustiveOptimizer%2FPlotExhaustiveOptimizer.ipynb
+ :target: https://mybinder.org/v2/gh/InsightSoftwareConsortium/ITKSphinxExamples/main?filepath=src%2FNumerics%2FOptimizers%2FExhaustiveOptimizer%2FPlotExhaustiveOptimizer.ipynb
 
 Code
 ----
diff --git a/src/Registration/Common/MutualInformation/Documentation.rst b/src/Registration/Common/MutualInformation/Documentation.rst
index e7cab01d4..c0d73199c 100644
--- a/src/Registration/Common/MutualInformation/Documentation.rst
+++ b/src/Registration/Common/MutualInformation/Documentation.rst
@@ -53,7 +53,7 @@ Jupyter Notebook
 ----------------
 
 .. image:: https://mybinder.org/badge_logo.svg
- :target: https://mybinder.org/v2/gh/InsightSoftwareConsortium/ITKSphinxExamples/master?filepath=src%2FRegistration%2FCommon%2FMutualInformation%2FMutualInformation.ipynb
+ :target: https://mybinder.org/v2/gh/InsightSoftwareConsortium/ITKSphinxExamples/main?filepath=src%2FRegistration%2FCommon%2FMutualInformation%2FMutualInformation.ipynb
 
 Code
 ----
diff --git a/src/Registration/Metricsv4/RegisterTwoPointSets/Documentation.rst b/src/Registration/Metricsv4/RegisterTwoPointSets/Documentation.rst
index 6205f0c83..735637f4c 100644
--- a/src/Registration/Metricsv4/RegisterTwoPointSets/Documentation.rst
+++ b/src/Registration/Metricsv4/RegisterTwoPointSets/Documentation.rst
@@ -54,7 +54,7 @@ Jupyter Notebook
 ----------------
 
 .. image:: https://mybinder.org/badge_logo.svg
-  :target: https://mybinder.org/v2/gh/InsightSoftwareConsortium/ITKSphinxExamples/master?filepath=src%2FRegistration%2FMetricsv4%2FRegisterTwoPointSets%2FRegisterTwoPointSets.ipynb
+  :target: https://mybinder.org/v2/gh/InsightSoftwareConsortium/ITKSphinxExamples/main?filepath=src%2FRegistration%2FMetricsv4%2FRegisterTwoPointSets%2FRegisterTwoPointSets.ipynb
 
 Code
 --------