When you are running a computation (that is not finished yet), and you reset the interface, by clicking on the menu button "File > New OI Image file", you land in an inconsistent state.
Indeed, the computation is not stopped, but the GUI display a sort of mix between "running" and "not running": the button Cancel cannot be clicked anymore, but it still displays Cancel instead of Run. Also, when the computation completes, no result is added to the table.