Confusion: "extract_outcome_data" function without without a filter for significant SNPs (whose p_value<5*10e-8)

[kamisama0101]

I found this question is more suitable for Discussions，so I put it on the Discussion Board.
(#626)

I got one confusion involving "extract_outcome_data" function in "TwoSampleMR" package: If is invalid to use non-genome wide significant SNPs from GWAS (whose p_value>5×10e-8) without the integration of a polygenic risk score for each individual, why was the"extract_outcome_data" function designed without a filter for significant SNPs? (whose p_value<5×10e-8). Will this design also cause any problem in analysis from analysis workflow on the TwoSampleMR official website？
https://mrcieu.github.io/TwoSampleMR/articles/perform_mr.html

Thank you for your help!