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DESCRIPTION
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Package: brainClass
Type: Package
Title: Transcriptional Data Guided fMRI Network Classification
Version: 0.1.0
Authors@R:
c(person("Mengbo", "Li",
email = "mengboli103@gmail.com",
role = c("aut", "cre")))
Maintainer: Mengbo Li <mengbo.li@sydney.edu.au>
Description: The brainclass R package is a toolkit that performs transcriptional
-data-guided fMRI network classification to link connectome with the brain
transcriptome. Via the strategic construction of feature groups which
incorporates biologically meaningful gene set information such as biological
pathways or gene ontology terms, the brainclass framework links predictive
functional connectivity features with the potentially involved biological
pathways, to bridge the gap between the functional biomarkers of
neurological disorders and their underpinning molecular mechanisms.
In addition, we also provide a post-hoc interpretation framework to enable
biologically meaningful interpretation for the functional edge selection
results by other existing fMRI network classification algorithms. The
proposed methods can be easily applied to task-based fMRI data, and the
selection of brain parcellation for brain network construction is entirely
flexible.
License: GPL-3
Encoding: UTF-8
LazyData: true
Depends: R (>= 3.6)
Imports: grpregOverlap, cvTools, stats, Matrix
Suggests: knitr, tidyverse, markdown
biocViews: Software, Classification, GeneExpression, Transcriptomics,
NetworkInference, Network, Regression
VignetteBuilder: knitr
URL: https://github.com/Mengbo-Li/brainClass
RoxygenNote: 7.1.1