Update dataset-open-targets.md

Author: mamtagiri

articles/open-datasets/dataset-open-targets.md

@@ -1,16 +1,16 @@
 ---
 title: Open Targets
-description: Learn how to use the 1000 Genomes dataset in Azure Open Datasets.
+description: Learn how to use the 1,000 Genomes dataset in Azure Open Datasets.
 ms.service: open-datasets
 ms.topic: sample
 ms.date: 04/16/2021
 ---
 
 # Open Targets
 
-The Open Targets Platform has built data resource that supports systematic identification and prioritisation of potential therapeutic drug targets.By integrating publicly available datasets including data generated by the Open Targets consortium, the Platform has built and scored target-disease associations to assist in drug target identification and prioritisation. It also integrates relevant annotation information about targets, diseases, phenotypes, and drugs, as well as their most relevant relationships.
+The Open Targets Platform is a data resource to facilitate the systematic identification and prioritization of potential therapeutic drug targets. This resource integrates publicly available datasets, including those datasets that are generated by the Open Targets consortium, to build and score target-disease associations, aiding in the identification and prioritization of drug targets. Additionally, it incorporates pertinent annotation information about targets, diseases, phenotypes, drugs, and their key relationships.
 
-The Open Targets Genetics highlights variant-centric statistical evidence to allow both prioritisation of candidate causal variants at trait-associated loci and identification of potential drug targets.It aggregates and integrates genetic associations curated from both literature and newly-derived loci from UK Biobank and FinnGen and also contains functional genomics data (e.g. chromatin conformation, chromatin interactions) and quantitative trait loci (eQTLs, pQTLs and sQTLs). Large-scale pipelines apply statistical fine-mapping across thousands of trait-associated loci to resolve association signals and link each variant to its proximal and distal target gene(s) using a Locus2Gene assessment. Integrated cross-trait colocalisation analyses and linking to detailed pharmaceutical compounds extend the capacity of Open Targets Genetics to explore drug repositioning opportunities and shared genetic architecture
+The Open Targets Genetics highlights variant-centric statistical evidence to allow both prioritization of candidate causal variants at trait-associated loci and identification of potential drug targets. It collects and combines genetic associations gathered from published literature as well as newly derived data from sources like UK Biobank and FinnGen. Additionally, it includes functional genomics information such as chromatin conformation and interactions, along with quantitative trait loci (eQTLs, pQTLs, and sQTLs). Large-scale pipelines apply statistical fine-mapping across thousands of trait-associated loci to resolve association signals and link each variant to its proximal and distal target genes using a 'Locus2Gene' assessment. Integrated cross-trait colocalisation analyses and linking to detailed pharmaceutical compounds extend the capacity of Open Targets Genetics to explore drug repositioning opportunities and shared genetic architecture.
 To read further about Open Targets Platform visit - [Open Targets Platform](https://platform.opentargets.org)
 To read further about Open Targets Genetics visit - [Open Targets Genetics](https://genetics.opentargets.org)
 [!INCLUDE [Open Dataset usage notice](../../includes/open-datasets-usage-note.md)]
@@ -36,7 +36,7 @@ West US 2: 'https://datasetopentargets.blob.core.windows.net/dataset'
 
 ## Use Terms
 
-Please refer to the data use terms as described [here](https://platform-docs.opentargets.org/licence)
+Please refer to the data use terms as described [here.](https://platform-docs.opentargets.org/licence)
 ## Contact
 
 [https://www.internationalgenome.org/contact](https://community.opentargets.org)