-You can define multiple virtual network interface cards (vNIC) for an Azure VM, each assigned to any subnet within the same virtual network as the primary vNIC. With the ability to have multiple vNICs, you can start to set up network traffic separation, if necessary. For example, client traffic is routed through the primary vNIC and backend traffic is routed through a second vNIC. Dependent on the type of VM there are different limitations for the number of vNICs a VM can have assigned. Exact details, functionality, and restrictions can be found in this articles - [Assign multiple IP addresses to virtual machines using the Azure portal](/azure/virtual-network/ip-services/virtual-network-multiple-ip-addresses-portal)
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