+> If you're using Group Policy to manage Microsoft Defender Antivirus settings, keep in mind that any changes made to tamper-protected settings are ignored. If you must make changes to a device and those changes are blocked by tamper protection, use [troubleshooting mode](enable-troubleshooting-mode.md) to temporarily disable tamper protection on the device. After troubleshooting mode ends, any changes made to tamper-protected settings are reverted to their configured state. To change the values on tamper-protected settings permanently you will need to disable tamper protection temporarily before turning it back on after the settings have changed. This obviously presents security risks and will not work on devices that are offline when tamper protect was temporarily disabled. This is a strong argument for using other management methods for Defender settings, like Intune, over Group Policy.
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