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NWB standard to integrate and leverage these resources for storing
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relevant metadata on the genotypes and genetic backgrounds of individual
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mice, linking neurophysiological data to the databases and literature that
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characterize the experimental animals. <br><br> <a href=''>[NDX
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Proposal]</a>
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characterize the experimental animals. <br><br>
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<a href='https://docs.google.com/document/d/12EVToclVEKXF8OP5hd6eaTYT6vj-ewhHYVM54u7h-tU/edit#heading=h.xk81rob2tb1l'>
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[NDX Proposal]</a>
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image: /images/genotype.png
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- title: Spatial coordinates representation
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content: Reporting of spatial coordinates within the brain is a complex problem,
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stimuli) within a spatial coordinate system. This type of standardization
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will facilitate the programmatic integration and comparison of data
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represented in NWB with other datasets that have been mapped to the same
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coordinate system. <br><br> <a href=''>[NDX Proposal]</a>
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coordinate system. <br><br>
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<a href='https://docs.google.com/document/u/0/d/13frfqavbj4e0T-cmR3B8zGanrEe-f74Sa_s1yp_0LcI/edit'>
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[NDX Proposal]</a>
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image: /images/spatial.png
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- title: Behavioral task representation
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content: Behavioral tasks are an increasingly important component in
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building a standard markup language (BEADL) to build state machine
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descriptions of task logic and control flow within a trial and across
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trials in a session, including tools for visualization, construction, and
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emulation of tasks from these machine-readable descriptions. <br><br> <a
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href=''>[NDX Proposal]</a>
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emulation of tasks from these machine-readable descriptions. <br><br>
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<a href='https://docs.google.com/document/d/1QQLbon-29Td5SblvB2AdWlGzCzgG7MNHloUD8C3tNdc/edit#heading=h.xk81rob2tb1l'>
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[NDX Proposal]</a>
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image: /images/behavioral.png
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- title: Spatial coordinates representation
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content: Reporting of spatial coordinates within the brain is a complex problem,
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requiring registration between data collected with multiple recording
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modalities (imaging, probes) and across brain preparations (in vivo whole
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brain, slice) with common reference atlases and controlled vocabularies.
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The focus of this working group is to create an NWB extension to capture
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spatial coordinate systems, spatial mappings between two systems, and the
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representation of objects (e.g. cells, probes, injections, and optogenetic
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stimuli) within a spatial coordinate system. This type of standardization
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will facilitate the programmatic integration and comparison of data
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represented in NWB with other datasets that have been mapped to the same
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coordinate system. <br><br> <a href=''>[NDX Proposal]</a>
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image: /images/spatial.png
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- title: External Working Groups
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bg_white: true
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content: NWB team members also participate in numerous external working groups.
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facilitate obtaining reproducible research and data sharing following the
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FAIR principles. In addition to data structures, the working group will
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discuss what experimental metadata is essential, and which formats and
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structures are appropriate for different metadata types. <br><br> <a
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href=''>Working Groups Page</a>
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structures are appropriate for different metadata types. <br><br>
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<a href='https://github.com/INCF/neuroscience-data-structure/'>Working Group Page</a>
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image: /images/incf-group.png
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- title: INCF Electrophysiology Stimulation Ontology Working Group
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bg_white: true
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protocols use very similar protocols with waveforms that have stereotyped
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profiles (e.g., long steps, ramps, chirps). This working group will also
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draft recommendations for representation in NWB of parameterized stimuli
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beyond 1-D waveforms. <br><br> <a href=''>Working Groups Page</a>
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beyond 1-D waveforms. <br><br>
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<a href='https://www.incf.org/sig/electrophysiology-stimulation-ontology-working-group'>
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Working Group Page</a>
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image: /images/incf-ontology-group.png
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- title: Standardization of data/file formats for simulation outputs in
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computational neuroscience
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data. Tasks for this working group include compiling a list of existing
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formats, defining evaluation criteria and evaluating the different
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formats, and identifying avenues for improving interoperability. <br><br>
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<a href=''>Source</a>, <a href=''>NDX</a>
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<a href='https://github.com/catalystneuro/ndx-simulation-output'>Source</a>,
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<a href='https://github.com/nwb-extensions/ndx-simulation-output-record'>NDX</a>
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image: /images/simulation.png
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past_groups:
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enable: true
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title: Outcomes
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content: The working group drafted an extension for the NWB schema that
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implements these tables for testing and evaluation of the proposed changes
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(see “<a href=''>Source</a>” “<a href=''>NDX</a>” “<a href=''>NDX
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Proposal</a>” “<a href=''>YouTube</a>”). The proposed extension underwent
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(see <a href='https://github.com/oruebel/ndx-icephys-meta'>Source</a>,
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<a href='https://github.com/nwb-extensions/ndx-icephys-meta-record'>NDX</a>,
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<a href='https://docs.google.com/document/d/1cAgsXv26BmQoVfa7Greyxs0oc4IGH-t5aJsm-AwUAAE/edit'>
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NDX Proposal</a>, <a href='https://www.youtube.com/watch?v=TClUoKA1pEU'>YouTube</a>
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). The proposed extension underwent
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community review and has been merged with NWB after completion of the
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review. The new structures developed by this working group have been
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released as part of <a href=''>NWB Schema version 2.4</a> and
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released as part of
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<a href='https://nwb-schema.readthedocs.io/en/latest/format_release_notes.html#aug-11-2021'>
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NWB Schema version 2.4</a> and
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corresponding PyNWB 2.0 and MatNWB 2.4.0.0. These new features are
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documented in the <a href=''>Intracellular electrophysiology tutorial</a>
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as part o PyNWB and <a href=''>AlignedDynamicTable tutorial</a> and <a
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href=''>AlignedDynmaicTable</a> schema as part of HDMF.
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documented in the
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<a href='https://pynwb.readthedocs.io/en/stable/tutorials/domain/plot_icephys.html#sphx-glr-tutorials-domain-plot-icephys-py'>
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Intracellular electrophysiology tutorial</a>
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as part of PyNWB and the
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<a href='https://hdmf.readthedocs.io/en/stable/tutorials/plot_aligneddynamictable.html#sphx-glr-tutorials-plot-aligneddynamictable-py'>
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AlignedDynamicTable tutorial</a> and
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<a href='https://hdmf-common-schema.readthedocs.io/en/latest/format.html#aligneddynamictable'>AlignedDynmaicTable</a>
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schema as part of HDMF.
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