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set version to v0.8.0
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README.md

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@@ -51,8 +51,9 @@ genefuse -r hg19.fasta -f genes/druggable.hg19.csv -1 genefuse.R1.fq.gz -2 genef
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## Reference genome
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The reference genome should be a single whole FASTA file containg all chromosome data. This file shouldn't be compressed. For human data, typicall `hg19/GRch37` or `hg38/GRch38` assembly is used, which can be downloaded from following sites:
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* `hg19/GRch37`: ftp://ftp.ncbi.nlm.nih.gov/sra/reports/Assembly/GRCh37-HG19_Broad_variant/Homo_sapiens_assembly19.fasta
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* `hg38/GRch38`: http://hgdownload.cse.ucsc.edu/goldenPath/hg38/bigZips/hg38.fa.gz Remember to decompress hg38.fa.gz since it is gzipped and is not supported currently.
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* `hg19/GRch37`: https://hgdownload.cse.ucsc.edu/goldenPath/hg19/bigZips/hg19.fa.gz
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* `hg38/GRch38`: https://hgdownload.cse.ucsc.edu/goldenpath/hg38/bigZips/hg38.fa.gz
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Remember to decompress hg19.fa.gz/hg38.fa.gz since it is gzipped and is not supported currently.
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## Fusion file
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The fusion file is a list of coordinated target genes together with their exons. A sample is:
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4. `genes/cancer.hg38.csv`: all COSMIC curated fusion genes (http://cancer.sanger.ac.uk/cosmic/fusion) based on `hg38/GRch38` reference assembly.
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Notes:
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* `genefuse` runs almost ~5X faster with `druggable` genes than `cancer` genes, since `druggable` genes are only a small subset of `cancer` genes. Use this one if you only care about the fusion related personalized medicine for cancers.
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* `genefuse` runs much faster with `druggable` genes than `cancer` genes, since `druggable` genes are only a small subset of `cancer` genes. Use this one if you only care about the fusion related personalized medicine for cancers.
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* The `cancer` genes should be enough for most cancer related studies, since all COSMIC curated fusion genes are included.
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* If you want to create a custom gene list, please follow the instructions given on next section.
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### Create a fusion file based on hg19 or hg38

src/common.h

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#ifndef COMMON_H
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#define COMMON_H
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#define FUSIONSCAN_VER "0.7.0"
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#define FUSIONSCAN_VER "0.8.0"
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#define _DEBUG true
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