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lines changed Original file line number Diff line number Diff line change 22Detect and visualize target mutations by scanning FastQ files directly
33* Ultra sensitive.
44* 50X+ faster than normal pipeline (i.e. BWA + Samtools + GATK/VarScan/Mutect).
5- * Very easy to use. Need nothing else. No alignment, no reference genome, no variant call, no...
6- * Include most actionable mutation points for cancer, like EGFR L858R, BRAF V600E...
5+ * Very easy to use and need nothing else. No alignment, no reference genome, no variant call, no...
6+ * Contains most actionable mutation points for cancer, like EGFR L858R, BRAF V600E...
77* Beautiful and informative HTML report with informative pileup visualization.
88* Multi-threading support.
9- * Support both single-end and pair-end data.
9+ * Supports both single-end and pair-end data.
1010* For pair-end data, MutScan will try to merge each pair, and do quality adjustment and error correction.
1111* Able to scan the mutations in a VCF file, which can be used to visualize called variants.
12- * Can be used to filter false-positive mutations, especially for INDEL.
12+ * Can be used to filter false-positive mutations. i.e. MutScan can handle highly repetive sequence to avoid false INDEL calling .
1313
1414# Sample report
1515http://opengene.org/MutScan/report.html
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