Updated plots

Author: pgleeson

NMC/NeuroML2/channel_summary/Ca_HVA.inf.png

@@ -10,7 +10,10 @@
             <p style="font-size:80%;font-family:arial"><a href="../NaTa_t.channel.nml">NaTa_t.channel.nml</a></p>
             <p style="font-size:80%;background-color:#1E90FF;"><b>Ion: na</b></p>
             <p style="font-size:80%;font-family:arial">g = gmax * m<sup>3</sup> * h </p><br/>
-            <p style="font-size:80%;font-family:arial">Fast inactivating Na+ current</p><br/>
+            <p style="font-size:80%;font-family:arial">Fast inactivating Na+ current
+            
+Comment from original mod file: 
+:Reference :Colbert and Pan 2002</p><br/>
         </td>
         <td>
         <a href="NaTa_t.inf.png"><img alt="NaTa_t steady state" src="NaTa_t.inf.png" height="300"/></a>
@@ -25,7 +28,13 @@
             <p style="font-size:80%;font-family:arial"><a href="../Nap_Et2.channel.nml">Nap_Et2.channel.nml</a></p>
             <p style="font-size:80%;background-color:#1E90FF;"><b>Ion: na</b></p>
             <p style="font-size:80%;font-family:arial">g = gmax * m<sup>3</sup> * h </p><br/>
-            <p style="font-size:80%;font-family:arial">Persistent Na+ current</p><br/>
+            <p style="font-size:80%;font-family:arial">Persistent Na+ current
+            
+Comment from original mod file: 
+:Comment : mtau deduced from text (said to be 6 times faster than for NaTa)
+:Comment : so I used the equations from NaT and multiplied by 6
+:Reference : Modeled according to kinetics derived from Magistretti and Alonso 1999
+:Comment: corrected rates using q10 = 2.3, target temperature 34, orginal 21</p><br/>
         </td>
         <td>
         <a href="Nap_Et2.inf.png"><img alt="Nap_Et2 steady state" src="Nap_Et2.inf.png" height="300"/></a>
@@ -55,7 +64,13 @@
             <p style="font-size:80%;font-family:arial"><a href="../K_Tst.channel.nml">K_Tst.channel.nml</a></p>
             <p style="font-size:80%;background-color:#CD5C5C;"><b>Ion: k</b></p>
             <p style="font-size:80%;font-family:arial">g = gmax * m<sup>4</sup> * h </p><br/>
-            <p style="font-size:80%;font-family:arial">Fast inactivating K+ current</p><br/>
+            <p style="font-size:80%;font-family:arial">Fast inactivating K+ current
+            
+Comment from original mod file: 
+:Comment : The transient component of the K current
+:Reference : :		Voltage-gated K+ channels in layer 5 neocortical pyramidal neurones from young rats:subtypes and gradients,Korngreen and Sakmann, J. Physiology, 2000
+:Comment : shifted -10 mv to correct for junction potential
+:Comment: corrected rates using q10 = 2.3, target temperature 34, orginal 21</p><br/>
         </td>
         <td>
         <a href="K_Tst.inf.png"><img alt="K_Tst steady state" src="K_Tst.inf.png" height="300"/></a>
@@ -70,7 +85,13 @@
             <p style="font-size:80%;font-family:arial"><a href="../K_Pst.channel.nml">K_Pst.channel.nml</a></p>
             <p style="font-size:80%;background-color:#CD5C5C;"><b>Ion: k</b></p>
             <p style="font-size:80%;font-family:arial">g = gmax * m<sup>2</sup> * h </p><br/>
-            <p style="font-size:80%;font-family:arial">Slow inactivating K+ current</p><br/>
+            <p style="font-size:80%;font-family:arial">Slow inactivating K+ current
+            
+Comment from original mod file: 
+:Comment : The persistent component of the K current
+:Reference : :		Voltage-gated K+ channels in layer 5 neocortical pyramidal neurones from young rats:subtypes and gradients,Korngreen and Sakmann, J. Physiology, 2000
+:Comment : shifted -10 mv to correct for junction potential
+:Comment: corrected rates using q10 = 2.3, target temperature 34, orginal 21</p><br/>
         </td>
         <td>
         <a href="K_Pst.inf.png"><img alt="K_Pst steady state" src="K_Pst.inf.png" height="300"/></a>
@@ -85,7 +106,10 @@
             <p style="font-size:80%;font-family:arial"><a href="../SKv3_1.channel.nml">SKv3_1.channel.nml</a></p>
             <p style="font-size:80%;background-color:#CD5C5C;"><b>Ion: k</b></p>
             <p style="font-size:80%;font-family:arial">g = gmax * m </p><br/>
-            <p style="font-size:80%;font-family:arial">Fast, non inactivating K+ current</p><br/>
+            <p style="font-size:80%;font-family:arial">Fast, non inactivating K+ current
+            
+Comment from original mod file: 
+:Reference : :		Characterization of a Shaw-related potassium channel family in rat brain, The EMBO Journal, vol.11, no.7,2473-2486 (1992)</p><br/>
         </td>
         <td>
         <a href="SKv3_1.inf.png"><img alt="SKv3_1 steady state" src="SKv3_1.inf.png" height="300"/></a>
@@ -100,7 +124,11 @@
             <p style="font-size:80%;font-family:arial"><a href="../SK_E2.channel.nml">SK_E2.channel.nml</a></p>
             <p style="font-size:80%;background-color:#CD5C5C;"><b>Ion: k</b></p>
             <p style="font-size:80%;font-family:arial">g = gmax * z </p><br/>
-            <p style="font-size:80%;font-family:arial">Small-conductance, Ca2+ activated K+ current</p><br/>
+            <p style="font-size:80%;font-family:arial">Small-conductance, Ca2+ activated K+ current
+            
+Comment from original mod file: 
+: SK-type calcium-activated potassium current
+: Reference : Kohler et al. 1996</p><br/>
         </td>
         <td>
         <a href="SK_E2.inf.png"><img alt="SK_E2 steady state" src="SK_E2.inf.png" height="300"/></a>
@@ -115,7 +143,13 @@
             <p style="font-size:80%;font-family:arial"><a href="../Ca_LVAst.channel.nml">Ca_LVAst.channel.nml</a></p>
             <p style="font-size:80%;background-color:#8FBC8F;"><b>Ion: ca</b></p>
             <p style="font-size:80%;font-family:arial">g = gmax * m<sup>2</sup> * h </p><br/>
-            <p style="font-size:80%;font-family:arial">Low voltage activated Ca2+ current</p><br/>
+            <p style="font-size:80%;font-family:arial">Low voltage activated Ca2+ current
+            
+Comment from original mod file: 
+Note: mtau is an approximation from the plots
+:Reference : :		Avery and Johnston 1996, tau from Randall 1997
+:Comment: shifted by -10 mv to correct for junction potential
+:Comment: corrected rates using q10 = 2.3, target temperature 34, orginal 21</p><br/>
         </td>
         <td>
         <a href="Ca_LVAst.inf.png"><img alt="Ca_LVAst steady state" src="Ca_LVAst.inf.png" height="300"/></a>
@@ -130,7 +164,10 @@
             <p style="font-size:80%;font-family:arial"><a href="../Ca_HVA.channel.nml">Ca_HVA.channel.nml</a></p>
             <p style="font-size:80%;background-color:#8FBC8F;"><b>Ion: ca</b></p>
             <p style="font-size:80%;font-family:arial">g = gmax * m<sup>2</sup> * h </p><br/>
-            <p style="font-size:80%;font-family:arial">High voltage activated Ca2+ current</p><br/>
+            <p style="font-size:80%;font-family:arial">High voltage activated Ca2+ current. 
+            
+Comment from original mod file: 
+Reuveni, Friedman, Amitai, and Gutnick, J.Neurosci. 1993</p><br/>
         </td>
         <td>
         <a href="Ca_HVA.inf.png"><img alt="Ca_HVA steady state" src="Ca_HVA.inf.png" height="300"/></a>
@@ -145,7 +182,10 @@
             <p style="font-size:80%;font-family:arial"><a href="../Ih.channel.nml">Ih.channel.nml</a></p>
             <p style="font-size:80%;background-color:#A9A9A9;"><b>Ion: hcn</b></p>
             <p style="font-size:80%;font-family:arial">g = gmax * m </p><br/>
-            <p style="font-size:80%;font-family:arial">Non-specific cation current</p><br/>
+            <p style="font-size:80%;font-family:arial">Non-specific cation current
+            
+Comment from original mod file: 
+Reference : :		Kole,Hallermann,and Stuart, J. Neurosci. 2006</p><br/>
         </td>
         <td>
         <a href="Ih.inf.png"><img alt="Ih steady state" src="Ih.inf.png" height="300"/></a>