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NeuroML2/osbSessions/3.html

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<p><strong>What are the properties of the cell?</strong></p>
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<p>Now let's focus on the cell model. The cell is named <strong><span style="color:#ff5a02">L23_cADpyr</span> </strong>
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<p>Now let's focus on the cell model. The cell is named <strong style="color:#ff5a02">L23_cADpyr</strong>
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(Layer 2/3 continuous accommodating pyramidal cell).</p>
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<p>Selecting this in the <strong> <span style="color:#ff5a02">Model Description</span></strong> widget displays the properties of the cell.
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<p>Selecting this in the <strong style="color:#ff5a02">Model Description</strong> widget displays the properties of the cell.
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There are <strong>1148 segments</strong> (based on the 3D points/radii from the neuronal reconstruction) and
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<strong>132 segment groups</strong> consisting of sections of neurites between branch points as well as larger segment groups such as basal dendrites, axon, etc.</p>
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<p><i class="fa fa-exclamation-circle" aria-hidden="true" style="color:#dd0000"></i> Click on
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<strong> <span style="color:#ff5a02">Highlight cell regions</span></strong> in the widget (link is under
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<strong style="color:#ff5a02">Highlight cell regions</strong> in the widget (link is under
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<strong>Click to apply colouring to the cell morphology</strong>). The cell should change color indicating the different regions:</p>
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<p>&nbsp;> <strong><span style="color:#0066FF">soma</span></strong> - consisting of a set of flat segments recreating the shape of the pyramidal cell soma</strong><br/>

NeuroML2/osbSessions/4.html

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&nbsp;> <strong><span style="color:#A9A9A9">Non specific </span></strong> </p>
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<p>The colored scales indicate the relative densities of the different conductances on the cell using a logarithmic scale.
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The <span style="color:#FF0000">red dot</span> (and the value printed on the right) shows the highest density present,
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and (if the conductance is not uniform across the cell) the <span style="color:#FFFF00">yellow dot</span> shows the lowest (non-zero) density.</p>
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The <strong style="color:#FF0000">red dot</strong> (and the value printed on the right) shows the highest density present,
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and (if the conductance is not uniform across the cell) the <strong style="color:#FFFF00">yellow dot</strong> shows the lowest (non-zero) density.</p>
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<p><i class="fa fa-exclamation-circle" aria-hidden="true" style="color:#dd0000"></i> Click on <strong> <span style="color:#ff5a02">NaTs2_t</span></strong>
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(near the top in the table). This highlights the distribution of this transient Na conductance, with a large concentration on the soma,
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<p><i class="fa fa-exclamation-circle" aria-hidden="true" style="color:#dd0000"></i> Click on <strong style="color:#ff5a02">NaTs2_t</strong>
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(on the left of the blue rows in the table). This highlights the distribution of this transient Na conductance, with a large concentration on the soma,
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a lower density on the apical dendrites, and zero conductance (shows as white on the cell) on the basal dendrites and axon.</p>
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<p><i class="fa fa-exclamation-circle" aria-hidden="true" style="color:#dd0000"></i> The highest densities present are for
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<strong><span style="color:#ff5a02">NaTa_t</span></strong> and <strong><span style="color:#ff5a02">K_Pst</span></strong>. Click on each of these in turn to show that these
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<strong style="color:#ff5a02">NaTa_t</strong> and <strong style="color:#ff5a02">K_Pst</strong>. Click on each of these in turn to show that these
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channels are only present on the axon (and result in this being the location of action potential initiation).</strong>
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<p><i class="fa fa-exclamation-circle" aria-hidden="true" style="color:#dd0000"></i> Click on <strong><span style="color:#ff5a02">Ih_apical</span></strong>
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<p><i class="fa fa-exclamation-circle" aria-hidden="true" style="color:#dd0000"></i> Click on <strong style="color:#ff5a02">Ih_apical</strong>
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to show how the conductance underlying the I<sub>h</sub> current varies on the apical dendrite from low for proximal locations to high at the apical tuft.</p>
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</div>

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