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Copy file name to clipboardExpand all lines: NeuroML2/osbSessions/15.html
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<p><strong>Changing the conductance densities</strong></p>
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<p>Try changing the conductance densities of some of the ion channels below. Some scenarios to try:</p>
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<p>Try changing the conductance densities of some of the ion channels and other cellular properties below. Some scenarios to try:</p>
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<p><strong> > Remove the high transient Na<sup>+</sup> conductance on the axon</strong><br/>
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Setting this value to 0 should lead to reduced firing frequency. However there is still a persistent Na<sup>+</sup> and so a gradual depolarisation leading to spiking...</p>
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Setting this value to 0 should lead to reduced firing frequency. However there is still a persistent Na<sup>+</sup>conductance on the axon and so a gradual depolarisation leading to spiking...</p>
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<p><strong> > Remove the persistent Na<sup>+</sup> conductance on the axon</strong><br/>
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This removes all spiking in the cell.</p>
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<p><strong> > Remove the persistent Na<sup>+</sup> conductance on the axon also</strong><br/>
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This removes all spiking in the cell</p>
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<p><strong> > Change the axial resistance of the cytoplasm</strong><br/>
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Increasing this (e.g. to 100 Ohm cm) will confine spiking to axon/soma and suppress spread to rest of cell.</p>
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Increasing this (e.g. to 100 Ohm cm) will confine spiking to axon/soma and suppress spread to rest of cell</p>
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