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Hi @lg2578, SaveImage resample image based on the spatial_shape (and original_affine) from metadata by default. Could you please try to set resample=False?

resample: whether to resample image (if needed) before saving the data array,
based on the `spatial_shape` (and `original_affine`) from metadata.

resample: bool = True,

Hope it can help you, thanks!

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@lg2578
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@wyli
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wyli Feb 27, 2023
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@lg2578
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@wyli
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wyli Feb 27, 2023
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Answer selected by lg2578
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