diff --git a/requirements.txt b/requirements.txt
index 7460f4f..12139bf 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -159,7 +159,7 @@ pyopenms==3.4.0
     #   pyprophet (setup.py)
 pyparsing==3.2.3
     # via matplotlib
-pypdf==6.4.0
+pypdf==6.6.0
     # via
     #   pyprophet
     #   pyprophet (setup.py)