"libzlib.so" cannot open shared object file: no such file or directory

[HongjianSun]

Hi,
I was using Rosetta to run this command in my HPC cluster, and found this error.
score_cmd = (
"/scratch/user/uqhsun9/tool/rosetta.source.release-371/main/rosetta_source/bin/score.linuxgccrelease "
"-database /scratch/user/uqhsun9/tool/rosetta.source.release-371/main/rosetta_database/ "
"-s /scratch/user/uqhsun9/tool/rosetta.source.release-371/structures/true_pdb/1MI5.pdb "
"-out:file:scorefile COM_score.sc "
"-extrachi_cutoff 1 "
"-ex1 -ex2 -ex3 "
"-score:weights weights_1.wts"
)

process = subprocess.Popen(score_cmd, shell=True)

error:
libzlib.so: cannot open shared object file: no such file or directory

I tried to load zlib in my HPC cluster, but the error exist. Also, I didn't find "libzlib.so" in the path of zlib. I don't know what I can do to solve this issue. Feel free to have any suggestions.

Thank you so much!
Nick

[roccomoretti]

Since you closed this, I presume you figured out the solution, but in case anyone else stumbles upon this discussion:

The one major external dependency that Rosetta has is zlib. You need to have that installed on your machine through your normal system install mechanism.

For things like an Ubuntu personal machine, that's normally doing something like apt install zlib1g-dev (check your distribution's packaging system for the development version of the zlib library.)

For a cluster, talk to your system adminstrators about the issue. If it's not installed globally, there may be a module you need to load in order to get the proper library package. (e.g. something like module load zlib, though the exact syntax will vary based on your cluster). Keep in mind that if you compile locally and then attempt to run on a remote cluster system, there might be some versioning issues.