diff --git a/packages/base/src/Keys.ts b/packages/base/src/Keys.ts
index 611665090c1e..729854ddcfcc 100644
--- a/packages/base/src/Keys.ts
+++ b/packages/base/src/Keys.ts
@@ -106,6 +106,10 @@ type KeyCodes = typeof KeyCodes[keyof typeof KeyCodes];
 
 const isEnter = (event: KeyboardEvent): boolean => (event.key ? event.key === "Enter" : event.keyCode === KeyCodes.ENTER) && !hasModifierKeys(event);
 
+const isEnterCtrl = (event: KeyboardEvent): boolean => (event.key ? event.key === "Enter" : event.keyCode === KeyCodes.ENTER) && checkModifierKeys(event, true, false, false);
+
+const isEnterAlt = (event: KeyboardEvent): boolean => (event.key ? event.key === "Enter" : event.keyCode === KeyCodes.ENTER) && checkModifierKeys(event, false, true, false);
+
 const isEnterShift = (event: KeyboardEvent): boolean => (event.key ? event.key === "Enter" : event.keyCode === KeyCodes.ENTER) && checkModifierKeys(event, false, false, true);
 
 const isCtrl = (event: KeyboardEvent): boolean => checkModifierKeys(event, true, false, false);
@@ -256,6 +260,8 @@ const isColon = (event: KeyboardEvent): boolean => ((event.key ? event.key === "
 
 export {
 	isEnter,
+	isEnterCtrl,
+	isEnterAlt,
 	isEnterShift,
 	isCtrl,
 	isSpace,
diff --git a/packages/fiori/src/NavigationMenuItem.ts b/packages/fiori/src/NavigationMenuItem.ts
index 0e5d7b73a171..eb02357b7bfb 100644
--- a/packages/fiori/src/NavigationMenuItem.ts
+++ b/packages/fiori/src/NavigationMenuItem.ts
@@ -5,7 +5,13 @@ import property from "@ui5/webcomponents-base/dist/decorators/property.js";
 import MenuItem from "@ui5/webcomponents/dist/MenuItem.js";
 import type SideNavigationItemDesign from "./types/SideNavigationItemDesign.js";
 import NavigationMenu from "./NavigationMenu.js";
-import { isSpace, isEnter } from "@ui5/webcomponents-base/dist/Keys.js";
+import {
+	isSpace,
+	isEnter,
+	isEnterShift,
+	isEnterCtrl,
+	isEnterAlt,
+} from "@ui5/webcomponents-base/dist/Keys.js";
 import type SideNavigationSelectableItemBase from "./SideNavigationSelectableItemBase.js";
 
 // Templates
@@ -167,7 +173,8 @@ class NavigationMenuItem extends MenuItem {
 			e.preventDefault();
 		}
 
-		if (isEnter(e)) {
+		// "Enter" + "Meta" is missing since it is often reserved by the operating system or window manager
+		if (isEnter(e) || isEnterShift(e) || isEnterCtrl(e) || isEnterAlt(e)) {
 			this._activate(e);
 		}
 
@@ -175,6 +182,7 @@ class NavigationMenuItem extends MenuItem {
 	}
 
 	_onkeyup(e: KeyboardEvent) {
+		// "Space" + modifier is often reserved by the operating system or window manager
 		if (isSpace(e)) {
 			this._activate(e);
 
diff --git a/packages/fiori/src/SideNavigation.ts b/packages/fiori/src/SideNavigation.ts
index 5dd80faf7720..bd2fa018c7d5 100644
--- a/packages/fiori/src/SideNavigation.ts
+++ b/packages/fiori/src/SideNavigation.ts
@@ -17,10 +17,7 @@ import {
 	isTablet,
 	isCombi,
 } from "@ui5/webcomponents-base/dist/Device.js";
-import {
-	isSpace,
-	isEnter,
-} from "@ui5/webcomponents-base/dist/Keys.js";
+
 import NavigationMode from "@ui5/webcomponents-base/dist/types/NavigationMode.js";
 import type SideNavigationItemBase from "./SideNavigationItemBase.js";
 import { isInstanceOfSideNavigationSelectableItemBase } from "./SideNavigationSelectableItemBase.js";
@@ -716,22 +713,6 @@ class SideNavigation extends UI5Element {
 		return this._isOverflow;
 	}
 
-	_onkeydownOverflow(e: KeyboardEvent) {
-		if (isSpace(e)) {
-			e.preventDefault();
-		}
-
-		if (isEnter(e)) {
-			this._handleOverflowClick();
-		}
-	}
-
-	_onkeyupOverflow(e: KeyboardEvent) {
-		if (isSpace(e)) {
-			this._handleOverflowClick();
-		}
-	}
-
 	captureRef(ref: HTMLElement & { associatedItem?: UI5Element} | null) {
 		if (ref) {
 			ref.associatedItem = this;
diff --git a/packages/fiori/src/SideNavigationItem.ts b/packages/fiori/src/SideNavigationItem.ts
index 78bc732e3b9c..137ad4b6d060 100644
--- a/packages/fiori/src/SideNavigationItem.ts
+++ b/packages/fiori/src/SideNavigationItem.ts
@@ -9,6 +9,9 @@ import {
 	isRight,
 	isSpace,
 	isEnter,
+	isEnterShift,
+	isEnterCtrl,
+	isEnterAlt,
 	isMinus,
 	isPlus,
 } from "@ui5/webcomponents-base/dist/Keys.js";
@@ -261,12 +264,14 @@ class SideNavigationItem extends SideNavigationSelectableItemBase {
 			return;
 		}
 
+		// "Space" + modifier is often reserved by the operating system or window manager
 		if (this.unselectable && isSpace(e)) {
 			this._toggle();
 			return;
 		}
 
-		if (this.unselectable && isEnter(e)) {
+		// "Enter" + "Meta" is missing since it is often reserved by the operating system or window manager
+		if (this.unselectable && (isEnter(e) || isEnterShift(e) || isEnterCtrl(e) || isEnterAlt(e))) {
 			this._toggle();
 		}
 
diff --git a/packages/fiori/src/SideNavigationSelectableItemBase.ts b/packages/fiori/src/SideNavigationSelectableItemBase.ts
index 8121113047f6..f570de7d790d 100644
--- a/packages/fiori/src/SideNavigationSelectableItemBase.ts
+++ b/packages/fiori/src/SideNavigationSelectableItemBase.ts
@@ -4,6 +4,9 @@ import event from "@ui5/webcomponents-base/dist/decorators/event-strict.js";
 import {
 	isSpace,
 	isEnter,
+	isEnterShift,
+	isEnterCtrl,
+	isEnterAlt,
 	isLeft,
 	isRight,
 } from "@ui5/webcomponents-base/dist/Keys.js";
@@ -255,7 +258,8 @@ class SideNavigationSelectableItemBase extends SideNavigationItemBase {
 			e.preventDefault();
 		}
 
-		if (isEnter(e)) {
+		// "Enter" + "Meta" is missing since it is often reserved by the operating system or window manager
+		if (isEnter(e) || isEnterShift(e) || isEnterCtrl(e) || isEnterAlt(e)) {
 			this._activate(e);
 		}
 
@@ -269,6 +273,7 @@ class SideNavigationSelectableItemBase extends SideNavigationItemBase {
 	}
 
 	_onkeyup(e: KeyboardEvent) {
+		// "Space" + modifier is often reserved by the operating system or window manager
 		if (isSpace(e)) {
 			this._activate(e);