Jump simulations are continuous time, discrete space, simulations (where the system's state, throughout the simulation, are the discrete copy numbers of each species). The system's state changes at discrete time points (in so-called jumps). For CRNs, these jumps correspond to the occurrence of individual reactions. Here, *stochastic chemical kinetics* describes how the reactions are distributed across time. Typically, the frequency of each reaction depends on its *propensity* (which in turn depends on its *rate* and *substrates*). These depend on the state of the system, and must thus be re-computed whenever the system's state changes. Hence, jump simulations' runtimes are heavily dependent on how frequently these propensities must be recomputed.
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