@@ -18,7 +18,7 @@ The <i>Domain Subsection</i> is organized as follows
1818< ; <strong >Viscosity</strong >> ;
1919<br ><br >
2020< ; <strong >Stimulus</strong > type=<i >stimulus_type</i >> ; <br >
21- [ <a href =" #stimulus_subsection " > Stimulus Subsection </a > ]
21+ [ <a href =" #domain_Stimulus_subsection " > Stimulus Subsection </a > ]
2222<br >
2323< ; <strong >Stimulus</strong >> ;
2424<br ><br >
@@ -56,7 +56,7 @@ The following sections list the parameters associated with a domain for a specif
5656<a href =" #domain_Electrophysiology_model " > Electrophysiology_model <a >
5757<a href =" #domain_Myocardial_zone " > Myocardial_zone <a >
5858<a href =" #domain_ODE_solver " > ODE_solver <a >
59- <a href =" #domain_Stimulus " > Stimulus <a >
59+ <a href =" #domain_Stimulus_subsection " > Stimulus <a >
6060<a href =" #domain_Time_step_for_integration " > Time_step_for_integration <a >
6161</pre >
6262
@@ -182,23 +182,24 @@ Convergence is deemed to occur when the size of the residual becomes sufficientl
182182<strong >< ; Anisotropic_conductivity> ; </strong > <i >vector</i > <nobr >
183183<strong >< ; /Anisotropic_conductivity> ; </strong >
184184</nobr ><br >
185- Sets the anisotropic conductivity constant.
185+ The anisotropic conductivity constant used to model the directional dependence of conduction velocity in cardiac tissue .
186186<br >
187187<section id =" domain_Backflow_stabilization_coefficient " >
188188<strong >< ; Backflow_stabilization_coefficient> ; </strong > <i >real</i > [ 0.2] <nobr >
189189<strong >< ; /Backflow_stabilization_coefficient> ; </strong >
190190</nobr ><br >
191191A parameter used to control flow reversal at outlet boundaries.
192192<br >
193+ <section id =" domain_Conductivity " >
193194<strong >< ; Conductivity> ; </strong > <i >real</i > [ 0.0] <nobr >
194195<strong >< ; /Conductivity> ; </strong >
195196</nobr ><br >
196- ?
197+ The thermal or diffusive conductivity within a domain.
197198<br >
198199<strong >< ; Continuity_stabilization_coefficient> ; </strong > <i >real</i > [ 0.0] <nobr >
199200<strong >< ; /Continuity_stabilization_coefficient> ; </strong >
200201</nobr ><br >
201- ?
202+ The stabilizing coefficient associated to the continuity equation in the Variational Multiscale Method.
202203<br >
203204<section id =" domain_density " >
204205<strong >< ; Density> ; </strong > <i >real</i > [ 0.5] <nobr >
@@ -239,7 +240,7 @@ Permissible values are
239240<strong >< ; Feedback_parameter_for_stretch_activated_currents> ; </strong > <i >real</i > [ 0.5] <nobr >
240241<strong >< ; /Feedback_parameter_for_stretch_activated_currents> ; </strong >
241242</nobr ><br >
242- ?
243+ The constant for stretch-activated currents (SACs) used in cardiac electrophysiology simulations.
243244<br >
244245<section id =" domain_Fluid_density " >
245246<strong >< ; Fluid_density> ; </strong > <i >real</i > [ 0.5] <nobr >
@@ -251,44 +252,44 @@ The density property for a fluid.
251252<strong >< ; Force_x> ; </strong > <i >real</i > [ 0.0] <nobr >
252253<strong >< ; /Force_x> ; </strong >
253254</nobr ><br >
254- ?
255+ The x-component of a body force applied to a domain.
255256<br >
256257<section id =" domain_Force_y " >
257258<strong >< ; Force_y> ; </strong > <i >real</i > [ 0.0] <nobr >
258259<strong >< ; /Force_y> ; </strong >
259260</nobr ><br >
260- ?
261+ The y-component of a body force applied to a domain.
261262<br >
262263<section id =" domain_Force_z " >
263264<strong >< ; Force_z> ; </strong > <i >real</i > [ 0.0] <nobr >
264265<strong >< ; /Force_z> ; </strong >
265266</nobr ><br >
266- ?
267+ The z-component of a body force applied to a domain.
267268<br >
268269<strong >< ; G_Na> ; </strong > <i >real</i > [ 14.838] <nobr >
269270<strong >< ; /G_Na> ; </strong >
270271</nobr ><br >
271- ?
272+ The maximal sodium conductance used in the TenTusscher-Panfilov Ventricular Myocyte Model.
272273<br >
273274<strong >< ; G_CaL> ; </strong > <i >real</i > [ 3.98E-5] <nobr >
274275<strong >< ; /G_CaL> ; </strong >
275276</nobr ><br >
276- ?
277+ The maximal calcium conductance used in the TenTusscher-Panfilov Ventricular Myocyte Model.
277278<br >
278279<strong >< ; G_Kr> ; </strong > <i >real</i > [ 0.153] <nobr >
279280<strong >< ; /G_Kr> ; </strong >
280281</nobr ><br >
281- ?
282+ The maximal rapid delayed rectifier potassium current used in the TenTusscher-Panfilov Ventricular Myocyte Model.
282283<br >
283284<strong >< ; G_Ks> ; </strong > <i >real</i > [ 0.392] <nobr >
284285<strong >< ; /G_Ks> ; </strong >
285286</nobr ><br >
286- ?
287+ The maximal rapid delayed rectifier sodium current used in the TenTusscher-Panfilov Ventricular Myocyte Model.
287288<br >
288289<strong >< ; G_to> ; </strong > <i >real</i > [ 0.294] <nobr >
289290<strong >< ; /G_to> ; </strong >
290291</nobr ><br >
291- ?
292+ The maximal transient outward current conductance used in the TenTusscher-Panfilov Ventricular Myocyte Model.
292293<br >
293294<strong >< ; Isotropic_conductivity> ; </strong > <i >real</i > [ 0.0] <nobr >
294295<strong >< ; /Isotropic_conductivity> ; </strong >
@@ -298,13 +299,13 @@ Sets the isotropic conductivity constant.
298299<strong >< ; Mass_damping> ; </strong > <i >real</i > [ 0.0] <nobr >
299300<strong >< ; /Mass_damping> ; </strong >
300301</nobr ><br >
301- ?
302+ The mass damping coefficient used to dissipate energy.
302303<br >
303304<section id =" domain_Momentum_stabilization_coefficient " >
304305<strong >< ; Momentum_stabilization_coefficient> ; </strong > <i >real</i > [ 0.0] <nobr >
305306<strong >< ; /Momentum_stabilization_coefficient> ; </strong >
306307</nobr ><br >
307- ?
308+ The stabilizing coefficient associated to the momentum equation in the Variational Multiscale Method.
308309<br >
309310<section id =" domain_Myocardial_zone " >
310311<strong >< ; Myocardial_zone> ; </strong > <i >string [ none] </i > <nobr >
@@ -324,9 +325,9 @@ Permissible values are
324325</nobr ><br >
325326The time integration method to solve the ODEs used to integrate activation models.
326327<ul style =" list-style-type :disc ;" >
327- <li > euler </li >
328- <li > implicit - </li >
329- <li > runge - </li >
328+ <li > euler - first-order Euler method </li >
329+ <li > implicit - second-order Crank–Nicolson method </li >
330+ <li > runge - fourth-order Runge-Kutte method </li >
330331</ul >
331332<br >
332333<strong >< ; Penalty_parameter> ; </strong > <i >real </i > [ 0.0] <nobr >
@@ -351,28 +352,29 @@ with the first error estimate calculated.
351352<strong >< ; Shell_thickness> ; </strong > <i >real</i > [ 0.0] <nobr >
352353<strong >< ; /Shell_thickness> ; </strong >
353354</nobr ><br >
354- ?
355+ The thickness of the shell elements in a domain.
355356<br >
356357<section id =" domain_Solid_density " >
357358<strong >< ; Solid_density> ; </strong > <i >real</i > [ 0.5] <nobr >
358359<strong >< ; /Solid_density> ; </strong >
359360</nobr ><br >
360361The density property for a solid.
361362<br >
363+ <section id =" domain_Source_term " >
362364<strong >< ; Source_term> ; </strong > <i >real</i > [ 0.0] <nobr >
363365<strong >< ; /Source_term> ; </strong >
364366</nobr ><br >
365- ?
367+ The volumetric source term (e.g. heat or dye) within a domain.
366368<br >
367369<strong >< ; tau_fi> ; </strong > <i >real</i > [ 0.110] <nobr >
368370<strong >< ; /tau_fi> ; </strong >
369371</nobr ><br >
370- ?
372+ The fast inward current time scale used in the Bueno-Orovio cell activation model.
371373<br >
372374<strong >< ; tau_si> ; </strong > <i >real</i > [ 1.88750] <nobr >
373375<strong >< ; /tau_si> ; </strong >
374376</nobr ><br >
375- ?
377+ The slow inward current time scale used in the Bueno-Orovio cell activation model.
376378<br >
377379<section id =" domain_Time_step_for_integration " >
378380<strong >< ; Time_step_for_integration> ; </strong > <i >real</i > [ 0.0] <nobr >
@@ -386,7 +388,7 @@ The time step size used to integrate activation models if different from simulat
386388<!-- ---------- Stimulus Subsection ----------- -->
387389<!-- ------------------------------------------ -->
388390
389- <h4 id =" stimulus_subsection " > Stimulus Subsection </h4 >
391+ <h4 id =" domain_Stimulus_subsection " > Stimulus Subsection </h4 >
390392The <i >Stimulus Subsection</i > of the <i >Domain Subsection</i > defines the stimulus
391393settings for pacemaker cells for a cardiac electrophysiology simulation.
392394
@@ -403,29 +405,29 @@ The <strong>Stimulus</strong> keyword adds stimulus settings to the enclosing do
403405<i >stimulus_type</i > attribute can be
404406
405407<ul style =" list-style-type :disc ;" >
406- <li > "Istim" - </li >
408+ <li > "Istim" - the applied stimulus is a source current and not a voltage source </li >
407409</ul >
408410
409411<h5 id =" stimulus_parameters " > Parameters </h5 >
410412<div class =" bc_param_div " >
411413<strong >< ; Amplitude> ; </strong > <i >real</i > [ 0.0] <nobr >
412414<strong >< ; /Amplitude> ; </strong >
413415</nobr ><br >
414- ?
416+ The stimulus amplitude.
415417<br >
416418<strong >< ; Cycle_length> ; </strong > <i >real</i > [ 0.0] <nobr >
417419<strong >< ; /Cycle_length> ; </strong >
418420</nobr ><br >
419- ?
421+ The stimulus cycle length.
420422<br >
421423<strong >< ; Duration> ; </strong > <i >real</i > [ 0.0] <nobr >
422424<strong >< ; /Duration> ; </strong >
423425</nobr ><br >
424- ?
426+ The stimulus duration.
425427<br >
426428<strong >< ; Start_time> ; </strong > <i >real</i > [ 0.0] <nobr >
427429<strong >< ; /Start_time> ; </strong >
428430</nobr ><br >
429- ?
431+ The stimulus start time.
430432<br >
431433</div >
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