diff --git a/src/wp-includes/pluggable.php b/src/wp-includes/pluggable.php
index 5edd0c760cbb2..6141669101494 100644
--- a/src/wp-includes/pluggable.php
+++ b/src/wp-includes/pluggable.php
@@ -294,10 +294,21 @@ function wp_mail( $to, $subject, $message, $headers = '', $attachments = array()
 		} else {
 			if ( ! is_array( $headers ) ) {
 				/*
-				 * Explode the headers out, so this function can take
-				 * both string headers and an array of headers.
+				 * Process headers and handle folding in a single pass.
+				 * Lines starting with whitespace (space or tab) are continuations of the previous line.
 				 */
-				$tempheaders = explode( "\n", str_replace( "\r\n", "\n", $headers ) );
+				$tempheaders        = array();
+				$normalized_headers = str_replace( "\r\n", "\n", $headers );
+
+				foreach ( explode( "\n", $normalized_headers ) as $header_line ) {
+					if ( ! empty( $tempheaders ) && isset( $header_line[0] ) && ( ' ' === $header_line[0] || "\t" === $header_line[0] ) ) {
+						// Continuation line - append to previous header.
+						$last_index                  = count( $tempheaders ) - 1;
+						$tempheaders[ $last_index ] .= "\n" . $header_line;
+					} else {
+						$tempheaders[] = $header_line;
+					}
+				}
 			} else {
 				$tempheaders = $headers;
 			}
diff --git a/tests/phpunit/tests/pluggable/wpMail.php b/tests/phpunit/tests/pluggable/wpMail.php
index 85e3b46f61a5b..4ed0aeba8fd5a 100644
--- a/tests/phpunit/tests/pluggable/wpMail.php
+++ b/tests/phpunit/tests/pluggable/wpMail.php
@@ -625,4 +625,24 @@ public function test_wp_mail_string_embeds() {
 			$this->assertStringContainsString( 'cid:' . $key, $mailer->get_sent()->body, 'The cid ' . $key . ' is not referenced in the mail body.' );
 		}
 	}
+
+	/**
+	 * Tests that wp_mail() correctly handles multiline From headers by unfolding them.
+	 *
+	 * @ticket 28473
+	 */
+	public function test_wp_mail_multiline_header() {
+		$headers  = 'From: =?UTF-8?B?0YLQtdGB0YIg0YLQtdGB0YIg0YLQtdGB0YIg0YLQtdGB0YIg0YLQtdGB0YIg?=';
+		$headers .= "\n =?UTF-8?B?0YLQtdGB0YIg0YLQtdGB0YI=?= <test@example.com>";
+		wp_mail( 'test@test.com', 'subject', 'message', $headers );
+
+		$mailer = tests_retrieve_phpmailer_instance();
+		// phpcs:disable WordPress.NamingConventions.ValidVariableName.UsedPropertyNotSnakeCase
+		$this->assertSame( 'test@example.com', $mailer->From );
+		$this->assertSame(
+			'=?UTF-8?B?0YLQtdGB0YIg0YLQtdGB0YIg0YLQtdGB0YIg0YLQtdGB0YIg0YLQtdGB0YIg?= =?UTF-8?B?0YLQtdGB0YIg0YLQtdGB0YI=?=',
+			$mailer->FromName
+		);
+		// phpcs:enable
+	}
 }