Is arboreto applicable to bulk RNA-Seq

[ZhangDengwei]

I understand the arboreto is designed for single-cell RNA-Seq, but how about the bulk RNAS-Seq data? If I apply arboreto to bulk RNA-Seq data set, is the result credible? Also, I am not familiar with this algorithm, what can I tell from the arboreto output, what is the meaning of importance between TF and target, and what threshold can be regarded as a valid regulation of TF against the target gene? Thanks in advance!