When "Generate separate debug info" is checked in Qt Creator, the atos lookup fails.
For starters, the .pri file needs QMAKE_CFLAGS_RELEASE_WITH_DEBUGINFO and QMAKE_CPPFLAGS_RELEASE_WITH_DEBUGINFO options modified like the others to turn off optimization.
Then the atos command needs to be changed to handle the external dSYM file (I think?).
I don't plan to do this, but if someone wants to take a swing at it, please feel free.