diff --git a/AmplifyPlugins/Predictions/AWSPredictionsPlugin/Liveness/SPI/LivenessStreamingURL.swift b/AmplifyPlugins/Predictions/AWSPredictionsPlugin/Liveness/SPI/LivenessStreamingURL.swift
index 93ee45ad3c..15c25593d2 100644
--- a/AmplifyPlugins/Predictions/AWSPredictionsPlugin/Liveness/SPI/LivenessStreamingURL.swift
+++ b/AmplifyPlugins/Predictions/AWSPredictionsPlugin/Liveness/SPI/LivenessStreamingURL.swift
@@ -7,8 +7,20 @@
 
 import Foundation
 
+private let isoPartitionBaseDomain: String = "csp.hci.ic.gov"
+private let defaultBaseDomain: String = "amazonaws.com"
+
 func streamingSessionURL(for region: String) throws -> URL {
-    let urlString = "wss://streaming-rekognition.\(region).amazonaws.com/start-face-liveness-session-websocket"
+
+    // Determine the base domain based on the region
+    let baseDomain: String
+    if region.lowercased().starts(with: "us-isof") {
+        baseDomain = isoPartitionBaseDomain
+    } else {
+        baseDomain = defaultBaseDomain
+    }
+
+    let urlString = "wss://streaming-rekognition.\(region).\(baseDomain)/start-face-liveness-session-websocket"
     guard let url = URL(string: urlString) else {
         throw FaceLivenessSessionError.invalidRegion
     }