diff --git a/sample-apps/python-manual-instrumentation-sample-app/requirements.txt b/sample-apps/python-manual-instrumentation-sample-app/requirements.txt
index 269efdc9..8a73a6f3 100644
--- a/sample-apps/python-manual-instrumentation-sample-app/requirements.txt
+++ b/sample-apps/python-manual-instrumentation-sample-app/requirements.txt
@@ -8,6 +8,6 @@ opentelemetry-instrumentation-requests==0.50b0
 opentelemetry-instrumentation-botocore==0.50b0
 opentelemetry-sdk-extension-aws==2.1.0
 opentelemetry-propagator-aws-xray==1.0.2
-protobuf==5.29.3
+protobuf==5.29.5
 PyYAML==6.0.2
 requests==2.32.3
\ No newline at end of file