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ok: Merge pull request #2874 from dpmccabe/add-depmap-omics-ccle
add depmap-omics-ccle yaml
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datasets/depmap-omics-ccle.yaml

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Name: The Cancer Dependency Map (DepMap) Cancer Cell Line Encyclopedia (CCLE) Dataset
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Description: This dataset consists of whole genome sequencing (WGS), whole exome sequencing (WES), and RNA sequencing files generated from ~1000 cancer cell lines described in Ghandi et al., 2019.
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Documentation: https://github.com/broadinstitute/depmap-omics-ccle
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Contact: https://forum.depmap.org
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ManagedBy: "[Cancer Data Science](https://cancerdatascience.org/), [Broad Institute](https://www.broadinstitute.org/)"
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UpdateFrequency: occasionally (as additional sequencings are generated for publicly-releasible CCLE models)
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Tags:
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- aws-pds
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- bam
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- biology
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- bioinformatics
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- cancer
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- genetic
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- genomic
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- Homo sapiens
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- life sciences
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- short read sequencing
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- transcriptomics
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- whole exome sequencing
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- whole genome sequencing
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License: https://grants.nih.gov/policy-and-compliance/policy-topics/sharing-policies/accessing-data/using-genomic-data
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Citation: Ghandi, Huang, Jané-Valbuena et al. Next-generation characterization of the Cancer Cell Line Encyclopedia. Nature 569, 503–508 (2019). https://doi.org/10.1038/s41586-019-1186-3
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Resources:
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- Description: CRAM/BAM files (and their corresponding CRAI/BAI indexes) for RNA, WES, and WGS samples released by The Cancer Dependency Map (DepMap) as part of the Cancer Cell Line Encyclopedia (CCLE) project
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ARN: arn:aws:s3:::depmap-omics-ccle
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Region: us-east-1
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Type: S3 Bucket
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- Description: Notifications for new depmap-omics-ccle data
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ARN: arn:aws:sns:us-east-1:019511184952:depmap-omics-ccle-object_created
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Region: us-east-1
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Type: SNS Topic
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DataAtWork:
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Tutorials:
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- Title: DepMap Omics CCLE data on the AWS Open Data Registry
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URL: https://github.com/broadinstitute/depmap-omics-ccle
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AuthorName: Devin McCabe
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Tools & Applications:
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- Title: The Cancer Dependency Map (DepMap)
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URL: https://depmap.org
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AuthorName: Arafeh, Shibue, Dempster et al.
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- Title: Cancer Cell Line Encyclopedia (CCLE)
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URL: https://sites.broadinstitute.org/ccle
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AuthorName: Ghandi, Huang, Jané-Valbuena et al.
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Publications:
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- Title: Next-generation characterization of the Cancer Cell Line Encyclopedia
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URL: https://www.nature.com/articles/s41586-019-1186-3
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AuthorName: Ghandi, Huang, Jané-Valbuena et al.
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- Title: The present and future of the Cancer Dependency Map
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URL: https://www.nature.com/articles/s41568-024-00763-x
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AuthorName: Arafeh, Shibue, Dempster et al.
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AuthorURL: https://depmap.org
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- Title: Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal
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URL: https://genomebiology.biomedcentral.com/articles/10.1186/s13059-023-03020-w
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AuthorName: Krill-Burger, Dempster, Borah et al.
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- Title: Genetic dependencies associated with transcription factor activities in human cancer cell lines
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URL: https://www.sciencedirect.com/science/article/pii/S2211124724005035
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AuthorName: Thatikonda, Supper, Wachter et al.
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- Title: Bridging the gap between cancer cell line models and tumours using gene expression data
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URL: https://www.nature.com/articles/s41416-021-01359-0
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AuthorName: Noorbakhsh, Vazquez & McFarland
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- Title: Integrated cross-study datasets of genetic dependencies in cancer
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URL: https://www.nature.com/articles/s41467-021-21898-7
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AuthorName: Pacini, Dempster, Boyle et al.
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- Title: Machine learning multi-omics analysis reveals cancer driver dysregulation in pan-cancer cell lines compared to primary tumors
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URL: https://www.nature.com/articles/s42003-022-04075-4
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AuthorName: Sanders, Chandra, Zebarjadi et al.
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- Title: "The Network Zoo: a multilingual package for the inference and analysis of gene regulatory networks"
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URL: https://link.springer.com/article/10.1186/s13059-023-02877-1
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AuthorName: Ben Guebila, Wang, Lopes-Ramos et al.
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ADXCategories:
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- Healthcare & Life Sciences Data

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