|
| 1 | +Name: RADIANT Public Data |
| 2 | +Description: > |
| 3 | + The Real-time Analysis and Discovery in Integrated And Networked Technologies (RADIANT) |
| 4 | + initiative seeks to develop an extensible, federated framework for rapid exchange of |
| 5 | + multimodal clinical and research data on behalf of accelerated discovery and patient impact. |
| 6 | + Coordination and implementation of initial RADIANT deployments will leverage a network of |
| 7 | + more than 35 partnered health care systems and participating patient families within the |
| 8 | + Children’s Brain Tumor Network (CBTN) and the Pediatric Neuro-Oncology Consortium (PNOC). |
| 9 | + This data set is composed of public multi-modal data provisioned by RADIANT. The initial |
| 10 | + bolus of data is from CBTN and consists of clinical data extracted/abstracted from |
| 11 | + electronic medical records, omic data such as genomics, transcriptomics and proteomics and |
| 12 | + radiology and pathology imaging data. Data are collected or generated as part of consent-based, |
| 13 | + IRB-approved observational or interventional studies with the goal of making it available |
| 14 | + globally to researchers across a broad number of disciplines. |
| 15 | +Documentation: https://cbtn.org/research-resources |
| 16 | + |
| 17 | +ManagedBy: "[The Center for Data-Driven Discovery in Biomedicine (D3b) at the Children's Hospital of Philadelphia](https://d3b.center/)" |
| 18 | +UpdateFrequency: | |
| 19 | + Data is updated on a regular basis by the RADIANT teams to make data available as |
| 20 | + rapidly as possible. |
| 21 | +Tags: |
| 22 | + - aws-pds |
| 23 | + - life sciences |
| 24 | + - cancer |
| 25 | + - genetic |
| 26 | + - genomic |
| 27 | + - transcriptomics |
| 28 | + - medical imaging |
| 29 | + - radiology |
| 30 | + - Homo sapiens |
| 31 | + - pediatric |
| 32 | + - whole genome sequencing |
| 33 | +License: "NIH Genomic Data Sharing Policy: https://grants.nih.gov/grants/guide/notice-files/not-od-14-124.html" |
| 34 | +Resources: |
| 35 | +- Description: "Children's Brain Tumor Network" |
| 36 | + ARN: arn:aws:s3:::opendata-chop-study-us-east-1-prd-sd-bhjxbdqk |
| 37 | + Region: us-east-1 |
| 38 | + Type: S3 Bucket |
| 39 | + ControlledAccess: https://cbtn.org/ |
| 40 | +DataAtWork: |
| 41 | + Tools & Applications: |
| 42 | + - Title: RADIANT Source Code |
| 43 | + URL: https://github.com/radiant-network |
| 44 | + AuthorName: RADIANT Team |
| 45 | + AuthorURL: https://github.com/radiant-network |
| 46 | + - Title: CAVATICA |
| 47 | + URL: http://cavatica.org |
| 48 | + AuthorName: Seven Bridges Genomics |
| 49 | + AuthorURL: http://www.sevenbridges.com |
| 50 | + - Title: PedcBioPortal |
| 51 | + URL: https://pedcbioportal.kidsfirstdrc.org |
| 52 | + AuthorName: cBioPortal |
| 53 | + AuthorURL: https://www.cbioportal.org/ |
| 54 | + - Title: Flywheel (CHOP D3b) |
| 55 | + URL: https://chop.flywheel.io |
| 56 | + AuthorName: Flywheel |
| 57 | + AuthorURL: https://flywheel.io/ |
| 58 | + Publications: |
| 59 | + - Title: "The children's brain tumor network (CBTN) - Accelerating research in pediatric central nervous system tumors through collaboration and open science." |
| 60 | + URL: https://pubmed.ncbi.nlm.nih.gov/36335802/ |
| 61 | + AuthorName: Jena V Lilly, Jo Lynne Rokita, Jennifer L Mason, et al. |
| 62 | + - Title: "The landscape of primary mismatch repair deficient gliomas in children, adolescents, and young adults: a multi-cohort study" |
| 63 | + URL: https://pubmed.ncbi.nlm.nih.gov/39701117/ |
| 64 | + AuthorName: Logine Negm, Jiil Chung, Liana Nobre, et al. |
| 65 | + - Title: "Multiparametric MRI along with machine learning predicts prognosis and treatment response in pediatric low-grade glioma" |
| 66 | + URL: https://pubmed.ncbi.nlm.nih.gov/39747214/ |
| 67 | + AuthorName: Anahita Gathi Kazerooni, Adam Kraya, Komal S Rathi, Meen Chul Kim, et al. |
| 68 | + - Title: "Multi-scale signaling and tumor evolution in high-grade gliomas" |
| 69 | + URL: https://pubmed.ncbi.nlm.nih.gov/38981438/ |
| 70 | + AuthorName: Jingxian Liu, Song Cao, Kathleen J Imback, et al. |
| 71 | + - Title: "Germline analysis of an international cohort of pediatric diffuse midline glioma patients" |
| 72 | + URL: https://pubmed.ncbi.nlm.nih.gov/40072012/ |
| 73 | + AuthorName: Marion K Mateos, Pamela Ajuyah, Noemi Fuentes-Bolanos, et al. |
| 74 | + - Title: "A road map for the treatment of pediatric diffuse midline glioma" |
| 75 | + URL: https://pubmed.ncbi.nlm.nih.gov/38039965/ |
| 76 | + AuthorName: Carl Koschmann, Wajd N Al-Holou, Marta M Alonso, et al. |
| 77 | + - Title: "Use of External Control Cohorts in Pediatric Brain Tumor Clinical Trials" |
| 78 | + URL: https://pubmed.ncbi.nlm.nih.gov/38394473/ |
| 79 | + AuthorName: Ashley S Margol, Annette M Molinaro, Arzu Onar-Thomas, et al. |
| 80 | + - Title: "OpenPBTA: The Open Pediatric Brain Tumor Atlas" |
| 81 | + URL: https://pubmed.ncbi.nlm.nih.gov/37492101/ |
| 82 | + AuthorName: Joshua A Shapiro, Krutika S Gaonkar, Stephanie J Spielman, et al. |
| 83 | + - Title: "Generation and multi-dimensional profiling of a childhood cancer cell line atlas defines new therapeutic opportunities" |
| 84 | + URL: https://pubmed.ncbi.nlm.nih.gov/37001527/ |
| 85 | + AuthorName: Claire Xin Sun, Paul Daniel, Gabrielle Bradshaw et al. |
0 commit comments