diff --git a/Orange/canvas/__main__.py b/Orange/canvas/__main__.py
index 975874e27d1..b42d0dc13aa 100644
--- a/Orange/canvas/__main__.py
+++ b/Orange/canvas/__main__.py
@@ -15,8 +15,8 @@
 from collections import defaultdict
 from datetime import date
 from urllib.request import urlopen, Request
+from packaging.version import Version
 
-import pkg_resources
 import yaml
 
 from AnyQt.QtGui import QColor, QDesktopServices, QIcon, QPalette
@@ -101,9 +101,8 @@ def run(self):
                     self.resultReady.emit(contents)
 
         def compare_versions(latest):
-            version = pkg_resources.parse_version
             skipped = settings.value('startup/latest-skipped-version', "", type=str)
-            if version(latest) <= version(current) or \
+            if Version(latest) <= Version(current) or \
                     latest == skipped:
                 return
 
@@ -187,8 +186,6 @@ def pull_notifications():
     if not check_notifs:
         return None
 
-    Version = pkg_resources.parse_version
-
     # create settings_dict for notif requirements purposes (read-only)
     spec = canvasconfig.spec + config.spec
     settings_dict = canvasconfig.Settings(defaults=spec, store=settings)
@@ -198,7 +195,7 @@ def pull_notifications():
                       if ep.dist is not None]
     installed = defaultdict(lambda: "-1")
     for addon in installed_list:
-        installed[addon.project_name] = addon.version
+        installed[addon.name] = addon.version
 
     # get set of already displayed notification IDs, stored in settings["notifications/displayed"]
     displayedIDs = literal_eval(settings.value("notifications/displayed", "set()", str))
diff --git a/Orange/canvas/config.py b/Orange/canvas/config.py
index fcef63a1b43..d3db38c5490 100644
--- a/Orange/canvas/config.py
+++ b/Orange/canvas/config.py
@@ -2,6 +2,8 @@
 Orange Canvas Configuration
 
 """
+import pkgutil
+
 import random
 import uuid
 import warnings
@@ -11,15 +13,16 @@
 from typing import Dict, Any, Optional, Iterable, List
 
 import packaging.version
-import pkg_resources
 import requests
 
 from AnyQt.QtGui import (
-    QPainter, QFont, QFontMetrics, QColor, QPixmap, QIcon, QGuiApplication
+    QPainter, QFont, QFontMetrics, QColor, QImage, QPixmap, QIcon,
+    QGuiApplication
 )
 from AnyQt.QtCore import Qt, QPoint, QRect, QSettings
 
 from orangecanvas import config as occonfig
+from orangecanvas.config import entry_points, EntryPoint
 from orangecanvas.utils.settings import config_slot
 from orangewidget.workflow import config
 from orangewidget.settings import set_widget_settings_dir_components
@@ -61,6 +64,11 @@
 spec = [config_slot(*t) for t in spec]
 
 
+def _pixmap_from_pkg_data(package, path, format):
+    contents = pkgutil.get_data(package, path)
+    return QPixmap.fromImage(QImage.fromData(contents, format))
+
+
 class Config(config.Config):
     """
     Orange application configuration
@@ -96,17 +104,16 @@ def application_icon():
         """
         Return the main application icon.
         """
-        path = pkg_resources.resource_filename(
-            __name__, "icons/orange-256.png"
+        return QIcon(
+            _pixmap_from_pkg_data(__package__, "icons/orange-256.png", "png")
         )
-        return QIcon(path)
 
     @staticmethod
     def splash_screen():
         splash_n = random.randint(1, 3)
-        path = pkg_resources.resource_filename(
-            __name__, f"icons/orange-splash-screen-{splash_n:02}.png")
-        pm = QPixmap(path)
+        pm = _pixmap_from_pkg_data(
+            __name__, f"icons/orange-splash-screen-{splash_n:02}.png", "png"
+        )
 
         version = Config.ApplicationVersion
         if version:
@@ -138,9 +145,9 @@ def widgets_entry_points():
         # Ensure the 'this' distribution's ep is the first. iter_entry_points
         # yields them in unspecified order.
         all_eps = sorted(
-            pkg_resources.iter_entry_points(WIDGETS_ENTRY),
+            entry_points(group=WIDGETS_ENTRY),
             key=lambda ep:
-                0 if ep.dist.project_name.lower() == "orange3" else 1
+                0 if ep.dist.name.lower() == "orange3" else 1
         )
         return iter(all_eps)
 
@@ -173,18 +180,18 @@ def core_packages():
 
     @staticmethod
     def examples_entry_points():
-        # type: () -> Iterable[pkg_resources.EntryPoint]
+        # type: () -> Iterable[EntryPoint]
         """
         Return an iterator over the entry points yielding 'Example Workflows'
         """
         # `iter_entry_points` yields them in unspecified order, so we order
         # them by name. The default is at the beginning, unless another
         # entrypoint precedes it alphabetically (e.g. starting with '!').
-        default_ep = pkg_resources.EntryPoint(
-            "000-Orange3", "Orange.canvas.workflows",
-            dist=pkg_resources.get_distribution("Orange3"))
+        default_ep = EntryPoint(
+            "000-Orange3", "Orange.canvas.workflows", "orange.widgets.tutorials",
+        )
 
-        all_ep = list(pkg_resources.iter_entry_points("orange.widgets.tutorials"))
+        all_ep = list(entry_points(group="orange.widgets.tutorials"))
         all_ep.append(default_ep)
         all_ep.sort(key=lambda x: x.name)
         return iter(all_ep)
diff --git a/Orange/tests/test_third_party.py b/Orange/tests/test_third_party.py
index aaad0cbcdf1..7657c385eac 100644
--- a/Orange/tests/test_third_party.py
+++ b/Orange/tests/test_third_party.py
@@ -1,11 +1,11 @@
 from unittest import TestCase
 
-from pkg_resources import parse_version
+from packaging.version import Version
 
 
 class TestPkgResources(TestCase):
     def test_parse_version(self):
-        self.assertGreater(parse_version('3.4.1'), parse_version('3.4.0'))
-        self.assertGreater(parse_version('3.4.1'), parse_version('3.4.dev'))
-        self.assertGreater(parse_version('3.4.1'), parse_version('3.4.1.dev'))
-        self.assertLess(parse_version('3.4.1'), parse_version('3.4.2.dev'))
+        self.assertGreater(Version('3.4.1'), Version('3.4.0'))
+        self.assertGreater(Version('3.4.1'), Version('3.4.dev'))
+        self.assertGreater(Version('3.4.1'), Version('3.4.1.dev'))
+        self.assertLess(Version('3.4.1'), Version('3.4.2.dev'))
diff --git a/Orange/util.py b/Orange/util.py
index 2a1581677de..d3a9d1073dc 100644
--- a/Orange/util.py
+++ b/Orange/util.py
@@ -6,11 +6,11 @@
 import datetime
 import math
 import functools
+import importlib.resources
 from contextlib import contextmanager
+from importlib.metadata import distribution
 from typing import TYPE_CHECKING, Callable, Union, Optional
 from weakref import WeakKeyDictionary
-
-import pkg_resources
 from enum import Enum as _Enum
 from functools import wraps, partial
 from operator import attrgetter
@@ -115,20 +115,18 @@ def resource_filename(path):
     """
     Return the resource filename path relative to the Orange package.
     """
-    return pkg_resources.resource_filename("Orange", path)
+    path = importlib.resources.files("Orange").joinpath(path)
+    return str(path)
 
 
 def get_entry_point(dist, group, name):
     """
     Load and return the entry point from the distribution.
-
-    Unlike `pkg_resources.load_entry_point`, this function does not check
-    for requirements. Calling this function is preferred because of developers
-    who experiment with different versions and have inconsistent configurations.
     """
-    dist = pkg_resources.get_distribution(dist)
-    ep = dist.get_entry_info(group, name)
-    return ep.resolve()
+    dist = distribution(dist)
+    eps = dist.entry_points.select(group=group, name=name)
+    ep = next(iter(eps))
+    return ep.load()
 
 
 def deprecated(obj):
diff --git a/Orange/widgets/__init__.py b/Orange/widgets/__init__.py
index 1b88afbf4ba..488995e50e4 100644
--- a/Orange/widgets/__init__.py
+++ b/Orange/widgets/__init__.py
@@ -4,17 +4,16 @@
 import os
 import sysconfig
 
-import pkg_resources
-
 from orangecanvas.registry import CategoryDescription
 from orangecanvas.registry.utils import category_from_package_globals
+from orangecanvas.utils.pkgmeta import get_distribution
 import orangewidget.workflow.discovery
 
 
 # Entry point for main Orange categories/widgets discovery
 def widget_discovery(discovery):
     # type: (orangewidget.workflow.discovery.WidgetDiscovery) -> None
-    dist = pkg_resources.get_distribution("Orange3")
+    dist = get_distribution("Orange3")
     pkgs = [
         "Orange.widgets.data",
         "Orange.widgets.visualize",
diff --git a/Orange/widgets/data/owpreprocess.py b/Orange/widgets/data/owpreprocess.py
index 872cfcd50cf..7a6e7342699 100644
--- a/Orange/widgets/data/owpreprocess.py
+++ b/Orange/widgets/data/owpreprocess.py
@@ -1,5 +1,5 @@
 from collections import OrderedDict
-import pkg_resources
+import importlib.resources
 
 import numpy
 
@@ -993,7 +993,8 @@ def __init__(self, name, qualname, category, description, viewclass):
 
 
 def icon_path(basename):
-    return pkg_resources.resource_filename(__name__, "icons/" + basename)
+    path = importlib.resources.files(__package__).joinpath("icons/" + basename)
+    return str(path)
 
 
 PREPROCESS_ACTIONS = [
diff --git a/Orange/widgets/tests/test_workflows.py b/Orange/widgets/tests/test_workflows.py
index 12a07bc9e32..630eee450b5 100644
--- a/Orange/widgets/tests/test_workflows.py
+++ b/Orange/widgets/tests/test_workflows.py
@@ -2,11 +2,12 @@
 from os import listdir, environ
 from os.path import isfile, join, dirname
 import unittest
-import pkg_resources
+from unittest import mock
 
 from AnyQt.QtTest import QTest
 
 from orangecanvas.registry import WidgetRegistry
+from orangecanvas.config import EntryPoint
 from orangewidget.workflow import widgetsscheme
 
 from Orange.canvas.config import Config
@@ -63,17 +64,17 @@ def test_scheme_examples(self):
                     QTest.qWait(0)
 
     def test_examples_order(self):
-        # register test entrypoints
-        dist_orange = pkg_resources.working_set.by_key['orange3']
-        ep_map = dist_orange.get_entry_map()
-        ep_first = pkg_resources.EntryPoint('!Testname', 'orangecontrib.any_addon.tutorials')
-        ep_last = pkg_resources.EntryPoint('exampletutorials', 'orangecontrib.other_addon.tutorials')
-        ep_map['orange.widgets.tutorials'] = {ep_first.name: ep_first, ep_last.name: ep_last}
+        ep_first = EntryPoint(
+            '!Testname', 'orangecontrib.any_addon.tutorials', '')
+        ep_last = EntryPoint(
+            'exampletutorials', 'orangecontrib.other_addon.tutorials', '')
 
-        ep_names = [point.name for point in Config.examples_entry_points()]
+        def entry_points(*_, **__):
+            return ep_first, ep_last
+
+        with mock.patch("Orange.canvas.config.entry_points", entry_points):
+            ep_names = [point.name for point in Config.examples_entry_points()]
         self.assertLess(ep_names.index(ep_first.name),
                         ep_names.index("000-Orange3"))
         self.assertLess(ep_names.index("000-Orange3"),
                         ep_names.index(ep_last.name))
-
-        del ep_map['orange.widgets.tutorials']
diff --git a/conda-recipe/meta.yaml b/conda-recipe/meta.yaml
index 4ab208c4bc7..9b65b01966e 100644
--- a/conda-recipe/meta.yaml
+++ b/conda-recipe/meta.yaml
@@ -37,8 +37,8 @@ requirements:
   run:
     - python
     # GUI requirements
-    - orange-canvas-core >=0.1.30,<0.2a
-    - orange-widget-base >=4.22.0
+    - orange-canvas-core >=0.2.0,<0.3a
+    - orange-widget-base >=4.23.0
     - anyqt >=0.2.0
     - pyqt >=5.12,!=5.15.1,<6.0
     - matplotlib-base >=3.2.0
@@ -66,7 +66,6 @@ requirements:
     - requests
     - scikit-learn >=1.3.0
     - scipy >=1.9
-    - serverfiles
     - setuptools >=51.0.0
     - xgboost >=1.7.4
     - xlsxwriter
diff --git a/i18n/si.jaml b/i18n/si.jaml
index b3775d00e4a..a17061b0c9d 100644
--- a/i18n/si.jaml
+++ b/i18n/si.jaml
@@ -364,8 +364,10 @@ canvas/config.py:
             canvas_settings_dir: false
         def `application_icon`:
             icons/orange-256.png: false
+            png: false
         def `splash_screen`:
             icons/orange-splash-screen-{splash_n:02}.png: false
+            png: false
             .: false
             Helvetica: false
             '#000000': false
diff --git a/pylintrc b/pylintrc
index 3f5d492f311..02e76ac05b2 100644
--- a/pylintrc
+++ b/pylintrc
@@ -332,4 +332,4 @@ int-import-graph=
 overgeneral-exceptions=builtins.Exception
 
 [isort]
-known-standard-library=pkg_resources
+known-standard-library=
diff --git a/requirements-core.txt b/requirements-core.txt
index d09fb9d0c9c..db1c8d514f2 100644
--- a/requirements-core.txt
+++ b/requirements-core.txt
@@ -12,6 +12,7 @@ networkx
 numpy>=1.20.0
 openpyxl
 openTSNE>=0.6.1,!=0.7.0  # 0.7.0 segfaults
+packaging
 pandas>=1.4.0,!=1.5.0,!=2.0.0
 pip>=18.0
 python-louvain>=0.13
@@ -20,7 +21,6 @@ requests
 scikit-learn>=1.3.0
 scipy>=1.9
 serverfiles		# for Data Sets synchronization
-setuptools>=51.0.0
 xgboost>=1.7.4
 # Reading Excel files
 xlrd>=1.2.0
diff --git a/requirements-gui.txt b/requirements-gui.txt
index a451226f7c4..e94cc275c9c 100644
--- a/requirements-gui.txt
+++ b/requirements-gui.txt
@@ -1,5 +1,5 @@
-orange-canvas-core>=0.1.30,<0.2a
-orange-widget-base>=4.22.0
+orange-canvas-core>=0.2a,<0.3a
+orange-widget-base>=4.23.0
 
 AnyQt>=0.2.0
 
diff --git a/tox.ini b/tox.ini
index 828c708e716..bb3b2dabc0a 100644
--- a/tox.ini
+++ b/tox.ini
@@ -36,8 +36,8 @@ deps =
     latest: https://github.com/biolab/orange-canvas-core/archive/refs/heads/master.zip#egg=orange-canvas-core
     latest: https://github.com/biolab/orange-widget-base/archive/refs/heads/master.zip#egg=orange-widget-base
     # GUI requirements
-    oldest: orange-canvas-core==0.1.30
-    oldest: orange-widget-base==4.22.0
+    oldest: orange-canvas-core==0.2.0
+    oldest: orange-widget-base==4.23.0
     oldest: AnyQt==0.2.0
     oldest: matplotlib==3.2.0
     oldest: pygments==2.8.0
@@ -64,7 +64,6 @@ deps =
     oldest: scikit-learn==1.3.0
     oldest: scipy==1.9
     # oldest: serverfiles
-    oldest: setuptools==51.0.0
     oldest: xgboost==1.7.4
     oldest: xlrd==1.2.0
     # oldest: xlsxwriter