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talks/_posts/2019-06-19-ohbm.md

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---
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layout: talk
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title: Using Topological Data Analysis to Capture and Quantify Transitions in Intrinsic Brain Activity in Individuals with Fragile X Syndrome
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image: /images/talks/ohbm2019.png
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date: Jun 19, 2019
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host: 2019 Organization of Human Brain Mapping Meeting, Rome, Italy
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speaker: Manish Saggar
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view: public
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link: https://www.pathlms.com/ohbm/courses/12238/sections/15843/video_presentations/138201
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abstract: In this talk Manish discusses how the application of TDA-based Mapper technique can facilitate examination of the organization of intrinsic brain activity in individuals with fragile X syndrome (FXS) at the single participant level. FXS is known to be the leading known single gene cause of Autism Spectrum Disorders. The resting state fMRI data were gathered from individuals with FXS and healthy controls. The severity of autism symptoms was assessed using Social Communication Questionnaire. Without collapsing data in space or time, we extracted a representation of overall brain dynamics for each participant using Mapper. The brain’s dynamical representation was later quantified using discrete-time finite-state Markov Chains and community detection tools from network science. Preliminary results suggest a relation between the average degree of a Markov Chain graph and severity of autism symptoms observed in individuals with FXS. Altogether, he presents one of the first applications of TDA-based methodologies to examine brain activity dynamics in clinical populations.
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# Abstract
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In this talk Manish discusses how the application of TDA-based Mapper technique can facilitate examination of the organization of intrinsic brain activity in individuals with fragile X syndrome (FXS) at the single participant level. FXS is known to be the leading known single gene cause of Autism Spectrum Disorders. The resting state fMRI data were gathered from individuals with FXS and healthy controls. The severity of autism symptoms was assessed using Social Communication Questionnaire. Without collapsing data in space or time, we extracted a representation of overall brain dynamics for each participant using Mapper. The brain’s dynamical representation was later quantified using discrete-time finite-state Markov Chains and community detection tools from network science. Preliminary results suggest a relation between the average degree of a Markov Chain graph and severity of autism symptoms observed in individuals with FXS. Altogether, he presents one of the first applications of TDA-based methodologies to examine brain activity dynamics in clinical populations.
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# Talk
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<div class="embed-responsive embed-responsive-16by9">
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<iframe width="560" height="315" src="https://www.pathlms.com/ohbm/courses/12238/sections/15843/video_presentations/138201" frameborder="0" allowfullscreen></iframe>
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</div>
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<br>

talks/_posts/2021-01-18-hpi.md

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layout: talk
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title: Characterizing cognitive states associated with creative thinking using (neuroimaging) network neuroscience and topological data analysis
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image: /images/talks/hpi2021.png
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date: Jan 18, 2021
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host: Neurodesign Lecture - Artificial Intelligence and the Neuroscience of Creativity (WT 2020/21)
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speaker: Manish Saggar
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view: public
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link: https://www.tele-task.de/lecture/video/8477/
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abstract: In this talk Manish discusses his research on the neuroscience of creativity. Specifically, he talked about (1) neuroscience of creativity using fMRI and Pictionary; (2) enhancing creativity using design thinking and associated neural correlates; (3) brain development and creative slump in 4th grade; and (4) neuroscience of team creativity and fMRI-hyperscanning; and (5) anchoring creativity into known cognitive constructs.
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# Abstract
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In this talk Manish discusses his research on the neuroscience of creativity. Specifically, he talked about (1) neuroscience of creativity using fMRI and Pictionary; (2) enhancing creativity using design thinking and associated neural correlates; (3) brain development and creative slump in 4th grade; and (4) neuroscience of team creativity and fMRI-hyperscanning; and (5) anchoring creativity into known cognitive constructs.
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# Talk
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<div class="embed-responsive embed-responsive-16by9">
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<iframe width="560" height="315" src="https://www.tele-task.de/lecture/video/8477/" frameborder="0" allowfullscreen></iframe>
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</div>
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<br>

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