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API for differential gene expression? #7432

@njwfish

Description

@njwfish

Description

The differential gene expression page on the CellxGene website is great. Is there some way to pull the same kind of results via a Python API?

Context

For a project it would be very useful to pull a large number of DEGs for different sets of cell types and tissues.

Impact

Doing this by hand is impractical so it would be great if this could be automated. It seems like it would be straight forward?

Alternatives you've considered

Downloading the whole of CellxGene and then writing a custom loader to iterate over the dataset to pull cell types, or pulling random cell types are both options but they are really not ideal.

Ideal behavior

I would hope to be able to simply replicate the behavior of the website via simple API requests in Python.

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