diff --git a/packages/wrangler/e2e/remote-binding/remote-bindings-api.test.ts b/packages/wrangler/e2e/remote-binding/remote-bindings-api.test.ts
new file mode 100644
index 000000000000..aeac42279d3d
--- /dev/null
+++ b/packages/wrangler/e2e/remote-binding/remote-bindings-api.test.ts
@@ -0,0 +1,266 @@
+import assert from "node:assert";
+import { resolve } from "node:path";
+import { afterAll, beforeAll, describe, expect, test } from "vitest";
+import { CLOUDFLARE_ACCOUNT_ID } from "../helpers/account-id";
+import { WranglerE2ETestHelper } from "../helpers/e2e-wrangler-test";
+import { generateResourceName } from "../helpers/generate-resource-name";
+import type {
+	Miniflare,
+	MiniflareOptions,
+	RemoteProxyConnectionString,
+	Response,
+} from "miniflare";
+
+// Note: the tests in this file are simple ones that check basic functionalities of the remote bindings programmatic APIs
+//       various other aspects of these APIs (e.g. different bindings, reloading capabilities) are indirectly tested when
+//       generally testing remote bindings
+
+describe.skipIf(!CLOUDFLARE_ACCOUNT_ID)(
+	"wrangler dev - remote bindings - programmatic API",
+	async () => {
+		const remoteWorkerName = generateResourceName();
+		const helper = new WranglerE2ETestHelper();
+
+		const { Miniflare } = await helper.importMiniflare();
+
+		const {
+			experimental_startRemoteProxySession: startRemoteProxySession,
+			experimental_maybeStartOrUpdateRemoteProxySession:
+				maybeStartOrUpdateRemoteProxySession,
+		} = await helper.importWrangler();
+
+		beforeAll(async () => {
+			await helper.seed(resolve(__dirname, "./workers"));
+			await helper.run(
+				`wrangler deploy remote-worker.js --name ${remoteWorkerName} --compatibility-date 2025-01-01`
+			);
+		}, 35_000);
+
+		afterAll(async () => {
+			await helper.run(`wrangler delete --name ${remoteWorkerName}`);
+		});
+
+		function getMfOptions(
+			remoteProxyConnectionString: RemoteProxyConnectionString
+		): MiniflareOptions {
+			return {
+				modules: true,
+				script: `
+				export default {
+					async fetch(req, env) {
+						const myServiceMsg = !env.MY_SERVICE ? null : await (await env.MY_SERVICE.fetch(req)).text();
+						return new Response("worker response: " + (myServiceMsg ?? ""));
+					}
+				}`,
+				serviceBindings: {
+					MY_SERVICE: {
+						name: remoteWorkerName,
+						remoteProxyConnectionString,
+					},
+				},
+			};
+		}
+
+		describe("startRemoteProxySession", () => {
+			test("base usage", async () => {
+				const remoteProxySession = await startRemoteProxySession({
+					MY_SERVICE: {
+						type: "service",
+						service: remoteWorkerName,
+					},
+				});
+				await remoteProxySession.ready;
+
+				const mf = new Miniflare(
+					getMfOptions(remoteProxySession.remoteProxyConnectionString)
+				);
+
+				const response = await timedDispatchFetch(mf);
+				const responseText = await response?.text();
+
+				expect(responseText).toEqual(
+					"worker response: Hello from a remote worker"
+				);
+
+				await mf.dispose();
+				await remoteProxySession.dispose();
+			});
+
+			test("user provided (incorrect but then corrected) auth data", async () => {
+				const remoteProxySession = await startRemoteProxySession(
+					{
+						MY_SERVICE: {
+							type: "service",
+							service: remoteWorkerName,
+						},
+					},
+					{
+						auth: {
+							accountId: CLOUDFLARE_ACCOUNT_ID,
+							apiToken: {
+								apiToken: "This is an incorrect API TOKEN!",
+							},
+						},
+					}
+				);
+				await remoteProxySession.ready;
+
+				const mf = new Miniflare(
+					getMfOptions(remoteProxySession.remoteProxyConnectionString)
+				);
+
+				const noResponse = await timedDispatchFetch(mf);
+				// We are unable to fetch from the worker since the remote connection is not correctly established
+				expect(noResponse).toBe(null);
+
+				assert(process.env.CLOUDFLARE_API_TOKEN);
+
+				const amendedRemoteProxySession = await startRemoteProxySession(
+					{
+						MY_SERVICE: {
+							type: "service",
+							service: remoteWorkerName,
+						},
+					},
+					{
+						auth: {
+							accountId: CLOUDFLARE_ACCOUNT_ID,
+							apiToken: {
+								apiToken: process.env.CLOUDFLARE_API_TOKEN,
+							},
+						},
+					}
+				);
+
+				await amendedRemoteProxySession.ready;
+
+				await mf.setOptions(
+					getMfOptions(amendedRemoteProxySession.remoteProxyConnectionString)
+				);
+
+				const response = await timedDispatchFetch(mf);
+				const responseText = await response?.text();
+
+				expect(responseText).toEqual(
+					"worker response: Hello from a remote worker"
+				);
+
+				await mf.dispose();
+				await remoteProxySession.dispose();
+				await amendedRemoteProxySession.dispose();
+			});
+		});
+
+		describe("maybeStartOrUpdateRemoteProxySession", () => {
+			test("base usage", async () => {
+				const proxySessionData = await maybeStartOrUpdateRemoteProxySession({
+					bindings: {
+						MY_SERVICE: {
+							type: "service",
+							service: remoteWorkerName,
+							experimental_remote: true,
+						},
+					},
+				});
+
+				assert(proxySessionData);
+
+				await proxySessionData.session.ready;
+
+				const mf = new Miniflare(
+					getMfOptions(proxySessionData.session.remoteProxyConnectionString)
+				);
+
+				const response = await timedDispatchFetch(mf);
+				const responseText = await response?.text();
+
+				expect(responseText).toEqual(
+					"worker response: Hello from a remote worker"
+				);
+
+				await mf.dispose();
+				await proxySessionData.session.dispose();
+			});
+
+			test("user provided (incorrect but then corrected) auth data", async () => {
+				let proxySessionData = await maybeStartOrUpdateRemoteProxySession(
+					{
+						bindings: {
+							MY_SERVICE: {
+								type: "service",
+								service: remoteWorkerName,
+								experimental_remote: true,
+							},
+						},
+					},
+					undefined,
+					{
+						accountId: CLOUDFLARE_ACCOUNT_ID,
+						apiToken: {
+							apiToken: "This is an incorrect API TOKEN!",
+						},
+					}
+				);
+
+				assert(proxySessionData);
+
+				await proxySessionData.session.ready;
+
+				const mf = new Miniflare(
+					getMfOptions(proxySessionData.session.remoteProxyConnectionString)
+				);
+
+				const noResponse = await timedDispatchFetch(mf);
+				// We are unable to fetch from the worker since the remote connection is not correctly established
+				expect(noResponse).toBe(null);
+
+				assert(process.env.CLOUDFLARE_API_TOKEN);
+
+				proxySessionData = await maybeStartOrUpdateRemoteProxySession(
+					{
+						bindings: {
+							MY_SERVICE: {
+								type: "service",
+								service: remoteWorkerName,
+								experimental_remote: true,
+							},
+						},
+					},
+					proxySessionData,
+					{
+						accountId: CLOUDFLARE_ACCOUNT_ID,
+						apiToken: {
+							apiToken: process.env.CLOUDFLARE_API_TOKEN,
+						},
+					}
+				);
+
+				assert(proxySessionData);
+
+				await mf.setOptions(
+					getMfOptions(proxySessionData.session.remoteProxyConnectionString)
+				);
+
+				const response = await timedDispatchFetch(mf);
+				const responseText = await response?.text();
+
+				expect(responseText).toEqual(
+					"worker response: Hello from a remote worker"
+				);
+
+				await mf.dispose();
+				await proxySessionData.session.dispose();
+			});
+		});
+	}
+);
+
+async function timedDispatchFetch(mf: Miniflare): Promise<Response | null> {
+	try {
+		return await mf.dispatchFetch("http://localhost/", {
+			signal: AbortSignal.timeout(5000),
+		});
+	} catch {
+		return null;
+	}
+}
diff --git a/packages/wrangler/src/api/remoteBindings/index.ts b/packages/wrangler/src/api/remoteBindings/index.ts
index c3f36847907e..c98d6a5c0fae 100644
--- a/packages/wrangler/src/api/remoteBindings/index.ts
+++ b/packages/wrangler/src/api/remoteBindings/index.ts
@@ -119,9 +119,6 @@ type WorkerConfigObject = {
 /**
  * Utility for potentially starting or updating a remote proxy session.
  *
- * It uses an internal map for storing existing remote proxy session indexed by worker names. If no worker name is provided
- * the remote proxy session won't be retrieved nor saved to/from the internal map.
- *
  * @param wranglerOrWorkerConfigObject either a file path to a wrangler configuration file or an object containing the name of
  *                                 the target worker alongside its bindings.
  * @param preExistingRemoteProxySessionData the optional data of a pre-existing remote proxy session if there was one, this