diff --git a/packages/wrangler/src/__tests__/deploy.test.ts b/packages/wrangler/src/__tests__/deploy.test.ts
index 8c2f844a9f02..bf2c55637307 100644
--- a/packages/wrangler/src/__tests__/deploy.test.ts
+++ b/packages/wrangler/src/__tests__/deploy.test.ts
@@ -12605,6 +12605,11 @@ export default{
 				"# Python vendor module 2\nprint('hello')"
 			);
 
+			await fs.promises.writeFile(
+				"python_modules/test.pyc",
+				"this shouldn't be deployed"
+			);
+
 			// Create a regular Python module
 			await fs.promises.writeFile(
 				"src/helper.py",
@@ -12614,12 +12619,15 @@ export default{
 			const expectedModules = {
 				"index.py": mainPython,
 				"helper.py": "# Helper module\ndef helper(): pass",
+				"python_modules/module1.so": "binary content for module 1",
+				"python_modules/module2.py": "# Python vendor module 2\nprint('hello')",
 			};
 
 			mockSubDomainRequest();
 			mockUploadWorkerRequest({
 				expectedMainModule: "index.py",
 				expectedModules,
+				excludedModules: ["python_modules/test.pyc"],
 			});
 
 			await runWrangler("deploy");
diff --git a/packages/wrangler/src/__tests__/helpers/mock-upload-worker.ts b/packages/wrangler/src/__tests__/helpers/mock-upload-worker.ts
index f9ef5d266f21..d6595af8c282 100644
--- a/packages/wrangler/src/__tests__/helpers/mock-upload-worker.ts
+++ b/packages/wrangler/src/__tests__/helpers/mock-upload-worker.ts
@@ -23,6 +23,7 @@ export function mockUploadWorkerRequest(
 		expectedType?: "esm" | "sw" | "none";
 		expectedBindings?: unknown;
 		expectedModules?: Record<string, string | null>;
+		excludedModules?: string[];
 		expectedCompatibilityDate?: string;
 		expectedCompatibilityFlags?: string[];
 		expectedMigrations?: CfWorkerInit["migrations"];
@@ -135,6 +136,9 @@ export function mockUploadWorkerRequest(
 		for (const [name, content] of Object.entries(expectedModules)) {
 			expect(await serialize(formBody.get(name))).toEqual(content);
 		}
+		for (const name of excludedModules) {
+			expect(formBody.get(name)).toBeNull();
+		}
 
 		if (useOldUploadApi) {
 			return HttpResponse.json(
@@ -173,6 +177,7 @@ export function mockUploadWorkerRequest(
 		expectedType = "esm",
 		expectedBindings,
 		expectedModules = {},
+		excludedModules = [],
 		expectedCompatibilityDate,
 		expectedCompatibilityFlags,
 		env = undefined,
diff --git a/packages/wrangler/src/deployment-bundle/find-additional-modules.ts b/packages/wrangler/src/deployment-bundle/find-additional-modules.ts
index 77a4641225fa..956583120d01 100644
--- a/packages/wrangler/src/deployment-bundle/find-additional-modules.ts
+++ b/packages/wrangler/src/deployment-bundle/find-additional-modules.ts
@@ -176,13 +176,30 @@ export async function findAdditionalModules(
 					pythonModulesDir,
 					parseRules(vendoredRules)
 				)
-			).map((m) => {
-				const prefixedPath = path.join("python_modules", m.name);
-				return {
-					...m,
-					name: prefixedPath,
-				};
-			});
+			)
+				.filter(
+					// Exclude certain file extensions to avoid bundling files that aren't
+					// necessary and which increase the size of the bundle considerably.
+					(m) =>
+						!m.name.endsWith(".pyc") &&
+						// Translation files
+						!m.name.endsWith(".po") &&
+						// Static files shouldn't be included
+						!m.name.endsWith(".svg") &&
+						!m.name.endsWith(".png") &&
+						!m.name.endsWith(".jpg") &&
+						!m.name.endsWith(".css") &&
+						!m.name.endsWith(".gz") &&
+						!m.name.endsWith(".txt") &&
+						!m.name.endsWith(".js")
+				)
+				.map((m) => {
+					const prefixedPath = path.join("python_modules", m.name);
+					return {
+						...m,
+						name: prefixedPath,
+					};
+				});
 
 			modules.push(...vendoredModules);
 		} else {