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| 1 | +import { type AnnotationFeature } from '@apollo-annotation/mst' |
| 2 | +import { type Frame, getFrame } from '@jbrowse/core/util' |
| 3 | +import { type BlockSet, type ContentBlock } from '@jbrowse/core/util/blockTypes' |
| 4 | +import { type Theme } from '@mui/material' |
| 5 | + |
| 6 | +import { type ApolloSessionModel, type HoveredFeature } from '../session' |
| 7 | + |
| 8 | +function getSeqRow( |
| 9 | + strand: 1 | -1 | undefined, |
| 10 | + bpPerPx: number, |
| 11 | +): number | undefined { |
| 12 | + if (bpPerPx > 1 || strand === undefined) { |
| 13 | + return |
| 14 | + } |
| 15 | + return strand === 1 ? 3 : 4 |
| 16 | +} |
| 17 | + |
| 18 | +function getTranslationRow(frame: Frame, bpPerPx: number) { |
| 19 | + const offset = bpPerPx <= 1 ? 2 : 0 |
| 20 | + switch (frame) { |
| 21 | + case 3: { |
| 22 | + return 0 |
| 23 | + } |
| 24 | + case 2: { |
| 25 | + return 1 |
| 26 | + } |
| 27 | + case 1: { |
| 28 | + return 2 |
| 29 | + } |
| 30 | + case -1: { |
| 31 | + return 3 + offset |
| 32 | + } |
| 33 | + case -2: { |
| 34 | + return 4 + offset |
| 35 | + } |
| 36 | + case -3: { |
| 37 | + return 5 + offset |
| 38 | + } |
| 39 | + } |
| 40 | +} |
| 41 | + |
| 42 | +function getLeftPx( |
| 43 | + feature: { min: number; max: number }, |
| 44 | + bpPerPx: number, |
| 45 | + offsetPx: number, |
| 46 | + block: ContentBlock, |
| 47 | +) { |
| 48 | + const blockLeftPx = block.offsetPx - offsetPx |
| 49 | + const featureLeftBpDistanceFromBlockLeftBp = block.reversed |
| 50 | + ? block.end - feature.max |
| 51 | + : feature.min - block.start |
| 52 | + const featureLeftPxDistanceFromBlockLeftPx = |
| 53 | + featureLeftBpDistanceFromBlockLeftBp / bpPerPx |
| 54 | + return blockLeftPx + featureLeftPxDistanceFromBlockLeftPx |
| 55 | +} |
| 56 | + |
| 57 | +function fillAndStrokeRect( |
| 58 | + ctx: CanvasRenderingContext2D, |
| 59 | + left: number, |
| 60 | + top: number, |
| 61 | + width: number, |
| 62 | + height: number, |
| 63 | + theme: Theme, |
| 64 | + selected = false, |
| 65 | +) { |
| 66 | + ctx.fillStyle = selected |
| 67 | + ? theme.palette.action.disabled |
| 68 | + : theme.palette.action.focus |
| 69 | + ctx.fillRect(left, top, width, height) |
| 70 | + ctx.strokeStyle = selected |
| 71 | + ? theme.palette.text.secondary |
| 72 | + : theme.palette.text.primary |
| 73 | + ctx.strokeStyle = theme.palette.text.primary |
| 74 | + ctx.strokeRect(left, top, width, height) |
| 75 | +} |
| 76 | + |
| 77 | +function drawHighlight( |
| 78 | + ctx: CanvasRenderingContext2D, |
| 79 | + feature: AnnotationFeature, |
| 80 | + bpPerPx: number, |
| 81 | + offsetPx: number, |
| 82 | + rowHeight: number, |
| 83 | + block: ContentBlock, |
| 84 | + theme: Theme, |
| 85 | + selected = false, |
| 86 | +) { |
| 87 | + const row = getSeqRow(feature.strand, bpPerPx) |
| 88 | + if (!row) { |
| 89 | + return |
| 90 | + } |
| 91 | + const left = getLeftPx(feature, bpPerPx, offsetPx, block) |
| 92 | + const width = feature.length / bpPerPx |
| 93 | + const top = row * rowHeight |
| 94 | + fillAndStrokeRect(ctx, left, top, width, rowHeight, theme, selected) |
| 95 | +} |
| 96 | + |
| 97 | +function drawCDSHighlight( |
| 98 | + ctx: CanvasRenderingContext2D, |
| 99 | + feature: AnnotationFeature, |
| 100 | + bpPerPx: number, |
| 101 | + offsetPx: number, |
| 102 | + rowHeight: number, |
| 103 | + block: ContentBlock, |
| 104 | + theme: Theme, |
| 105 | + selected = false, |
| 106 | +) { |
| 107 | + const parentFeature = feature.parent |
| 108 | + if (!parentFeature) { |
| 109 | + return |
| 110 | + } |
| 111 | + const cdsLocs = parentFeature.cdsLocations.find((loc) => { |
| 112 | + const min = loc.at(feature.strand === 1 ? 0 : -1)?.min |
| 113 | + const max = loc.at(feature.strand === 1 ? -1 : 0)?.max |
| 114 | + return feature.min === min && feature.max === max |
| 115 | + }) |
| 116 | + if (!cdsLocs) { |
| 117 | + return |
| 118 | + } |
| 119 | + for (const loc of cdsLocs) { |
| 120 | + const frame = getFrame(loc.min, loc.max, feature.strand ?? 1, loc.phase) |
| 121 | + const row = getTranslationRow(frame, bpPerPx) |
| 122 | + const left = getLeftPx(loc, bpPerPx, offsetPx, block) |
| 123 | + const top = row * rowHeight |
| 124 | + const width = (loc.max - loc.min) / bpPerPx |
| 125 | + fillAndStrokeRect(ctx, left, top, width, rowHeight, theme, selected) |
| 126 | + } |
| 127 | +} |
| 128 | + |
| 129 | +export function drawSequenceOverlay( |
| 130 | + canvas: HTMLCanvasElement, |
| 131 | + ctx: CanvasRenderingContext2D, |
| 132 | + hoveredFeature: HoveredFeature | undefined, |
| 133 | + selectedFeature: AnnotationFeature | undefined, |
| 134 | + rowHeight: number, |
| 135 | + theme: Theme, |
| 136 | + session: ApolloSessionModel, |
| 137 | + bpPerPx: number, |
| 138 | + offsetPx: number, |
| 139 | + dynamicBlocks: BlockSet, |
| 140 | +) { |
| 141 | + const { featureTypeOntology } = session.apolloDataStore.ontologyManager |
| 142 | + if (!featureTypeOntology) { |
| 143 | + throw new Error('featureTypeOntology is undefined') |
| 144 | + } |
| 145 | + for (const block of dynamicBlocks.contentBlocks) { |
| 146 | + ctx.save() |
| 147 | + ctx.beginPath() |
| 148 | + const blockLeftPx = block.offsetPx - offsetPx |
| 149 | + ctx.rect(blockLeftPx, 0, block.widthPx, canvas.height) |
| 150 | + ctx.clip() |
| 151 | + for (const feature of [ |
| 152 | + selectedFeature, |
| 153 | + hoveredFeature?.feature, |
| 154 | + ].filter<AnnotationFeature>((f) => f !== undefined)) { |
| 155 | + if (featureTypeOntology.isTypeOf(feature.type, 'CDS')) { |
| 156 | + drawCDSHighlight( |
| 157 | + ctx, |
| 158 | + feature, |
| 159 | + bpPerPx, |
| 160 | + offsetPx, |
| 161 | + rowHeight, |
| 162 | + block, |
| 163 | + theme, |
| 164 | + true, |
| 165 | + ) |
| 166 | + } else { |
| 167 | + drawHighlight( |
| 168 | + ctx, |
| 169 | + feature, |
| 170 | + bpPerPx, |
| 171 | + offsetPx, |
| 172 | + rowHeight, |
| 173 | + block, |
| 174 | + theme, |
| 175 | + true, |
| 176 | + ) |
| 177 | + } |
| 178 | + } |
| 179 | + ctx.restore() |
| 180 | + } |
| 181 | +} |
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