diff --git a/packages/cubejs-backend-native/src/python/runtime.rs b/packages/cubejs-backend-native/src/python/runtime.rs
index 00f0ea55fdb24..74535746ee693 100644
--- a/packages/cubejs-backend-native/src/python/runtime.rs
+++ b/packages/cubejs-backend-native/src/python/runtime.rs
@@ -3,6 +3,7 @@ use crate::python::neon_py::*;
 use crate::python::utils::PyAnyHelpers;
 use crate::tokio_runtime_node;
 use cubesql::CubeError;
+use futures::FutureExt;
 use log::{error, trace};
 use neon::prelude::*;
 use neon::types::Deferred;
@@ -11,6 +12,7 @@ use pyo3::prelude::*;
 use pyo3::types::{PyFunction, PyTuple};
 use std::fmt::Formatter;
 use std::future::Future;
+use std::panic;
 use std::pin::Pin;
 
 #[derive(Debug)]
@@ -129,30 +131,42 @@ impl PyRuntime {
     ) -> Result<(), CubeError> {
         let (fun, args, callback) = task.split();
 
-        let task_result = Python::with_gil(move |py| -> PyResult<PyScheduledFunResult> {
-            let mut prep_tuple = Vec::with_capacity(args.len());
-            let mut py_kwargs = None;
+        let task_block = panic::AssertUnwindSafe(|| {
+            Python::with_gil(move |py| -> PyResult<PyScheduledFunResult> {
+                let mut prep_tuple = Vec::with_capacity(args.len());
+                let mut py_kwargs = None;
 
-            for arg in args {
-                if arg.is_kwarg() {
-                    py_kwargs = Some(arg.into_py_dict(py)?);
-                } else {
-                    prep_tuple.push(arg.into_py(py)?);
+                for arg in args {
+                    if arg.is_kwarg() {
+                        py_kwargs = Some(arg.into_py_dict(py)?);
+                    } else {
+                        prep_tuple.push(arg.into_py(py)?);
+                    }
                 }
-            }
 
-            let py_args = PyTuple::new(py, prep_tuple);
-            let call_res = fun.call(py, py_args, py_kwargs)?;
+                let py_args = PyTuple::new(py, prep_tuple);
+                let call_res = fun.call(py, py_args, py_kwargs)?;
 
-            if call_res.is_coroutine()? {
-                let fut = pyo3_asyncio::tokio::into_future(call_res.as_ref(py))?;
-                Ok(PyScheduledFunResult::Poll(Box::pin(fut)))
-            } else {
-                Ok(PyScheduledFunResult::Ready(CLRepr::from_python_ref(
-                    call_res.as_ref(py),
-                )?))
-            }
+                if call_res.is_coroutine()? {
+                    let fut = pyo3_asyncio::tokio::into_future(call_res.as_ref(py))?;
+                    Ok(PyScheduledFunResult::Poll(Box::pin(fut)))
+                } else {
+                    Ok(PyScheduledFunResult::Ready(CLRepr::from_python_ref(
+                        call_res.as_ref(py),
+                    )?))
+                }
+            })
         });
+
+        let task_result = match panic::catch_unwind(task_block) {
+            Ok(Ok(r)) => Ok(r),
+            Ok(Err(err)) => Err(CubeError::user(format_python_error(err))),
+            Err(panic_payload) => Err(CubeError::panic_with_message(
+                panic_payload,
+                "Unexpected panic while calling python function",
+            )),
+        };
+
         let task_result = match task_result {
             Ok(r) => r,
             Err(err) => {
@@ -161,13 +175,12 @@ impl PyRuntime {
                         deferred.settle_with(
                             js_channel,
                             move |mut cx| -> NeonResult<Handle<JsError>> {
-                                cx.throw_from_python_error(err)
+                                cx.throw_error(err.to_string())
                             },
                         );
                     }
                     PyScheduledCallback::Channel(chan) => {
-                        let send_res =
-                            chan.send(Err(CubeError::internal(format_python_error(err))));
+                        let send_res = chan.send(Err(err));
                         if send_res.is_err() {
                             return Err(CubeError::internal(
                                 "Unable to send result back to consumer".to_string(),
@@ -185,31 +198,37 @@ impl PyRuntime {
                 let js_channel_to_move = js_channel.clone();
 
                 tokio::spawn(async move {
-                    let fut_res = fut.await;
+                    let safe_py_fut_poll = panic::AssertUnwindSafe(async {
+                        let fut_res = fut.await;
 
-                    let res = Python::with_gil(move |py| -> Result<CLRepr, PyErr> {
-                        let res = match fut_res {
-                            Ok(r) => CLRepr::from_python_ref(r.as_ref(py)),
-                            Err(err) => Err(err),
-                        };
+                        Python::with_gil(move |py| -> Result<CLRepr, PyErr> {
+                            let res = match fut_res {
+                                Ok(r) => CLRepr::from_python_ref(r.as_ref(py)),
+                                Err(err) => Err(err),
+                            };
 
-                        res
+                            res
+                        })
                     });
 
+                    let fut_res = match safe_py_fut_poll.catch_unwind().await {
+                        Ok(Ok(r)) => Ok(r),
+                        Ok(Err(err)) => Err(CubeError::internal(format_python_error(err))),
+                        Err(panic_payload) => Err(CubeError::panic_with_message(
+                            panic_payload,
+                            "Unexpected panic while polling python future",
+                        )),
+                    };
+
                     match callback {
                         PyScheduledCallback::NodeDeferred(deferred) => {
-                            deferred.settle_with(&js_channel_to_move, |mut cx| match res {
-                                Err(err) => cx.throw_error(format!("Python error: {}", err)),
+                            deferred.settle_with(&js_channel_to_move, |mut cx| match fut_res {
                                 Ok(r) => r.into_js(&mut cx),
+                                Err(err) => cx.throw_error(format!("{}", err)),
                             });
                         }
                         PyScheduledCallback::Channel(chan) => {
-                            let _ = match res {
-                                Ok(r) => chan.send(Ok(r)),
-                                Err(err) => {
-                                    chan.send(Err(CubeError::internal(format_python_error(err))))
-                                }
-                            };
+                            let _ = chan.send(fut_res);
                         }
                     }
                 });
diff --git a/rust/cubesql/cubesql/src/error.rs b/rust/cubesql/cubesql/src/error.rs
index e518f259b068e..d67b36f30fde7 100644
--- a/rust/cubesql/cubesql/src/error.rs
+++ b/rust/cubesql/cubesql/src/error.rs
@@ -51,12 +51,16 @@ impl CubeError {
     }
 
     pub fn panic(error: Box<dyn Any + Send>) -> Self {
+        Self::panic_with_message(error, "Unexpected panic")
+    }
+
+    pub fn panic_with_message(error: Box<dyn Any + Send>, message: &str) -> Self {
         if let Some(reason) = error.downcast_ref::<&str>() {
-            CubeError::internal(format!("Unexpected panic. Reason: {}", reason))
+            CubeError::internal(format!("{}. Reason: {}", message, reason))
         } else if let Some(reason) = error.downcast_ref::<String>() {
-            CubeError::internal(format!("Unexpected panic. Reason: {}", reason))
+            CubeError::internal(format!("{}. Reason: {}", message, reason))
         } else {
-            CubeError::internal("Unexpected panic without reason".to_string())
+            CubeError::internal(format!("{} without reason", message))
         }
     }
 }